Results 71 to 80 of about 1,494,008 (310)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Characterization and administration of bone marrow-derived mesenchymal stem cells in an animal model of congenital hydrocephalus [PDF]
, 2015 Bone marrow-derived mesenchymal stem cells (BM-MSC) are considered as a potential therapeutic tool in neurodegenerative diseases, due to their ability to migrate to degenerated tissues and the production of growth factors.
Cifuentes, Manuel +6 more
core
Inverse Scattering and the Geroch Group
, 2013 We study the integrability of gravity-matter systems in D=2 spatial dimensions with matter related to a symmetric space G/K using the well-known linear systems of Belinski-Zakharov (BZ) and Breitenlohner-Maison (BM).
Katsimpouri, Despoina +2 more
core +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Journal of Thoracic Oncology, 2014 Background: Bone metastasis (BM) is a frequent complication in patients with advanced lung cancer and it causes skeletal-related events (SREs). Our study aim is to prospectively investigate the incidence of BM, incidence and types of SRE, and predictive ...
N. Katakami +12 more
semanticscholar +1 more source
On projections of arbitrary lattices
, 2013 In this paper we prove that given any two point lattices $\Lambda_1 \subset \mathbb{R}^n$ and $ \Lambda_2 \subset \nobreak \mathbb{R}^{n-k}$, there is a set of $k$ vectors $\bm{v}_i \in \Lambda_1$ such that $\Lambda_2$ is, up to similarity, arbitrarily ...
Antonio Campello +16 more
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Bone marrow-derived mesenchymal stem cells characterization and transplantation in an animal model of congenital hydrocephalus [PDF]
, 2015 Congenital hydrocephalus is a disorder presenting a degeneration of the periventricular cerebral parenchyma and the white matter, which causes significant mortality and life-long neurological complications.
Cifuentes, Manuel +6 more
core
, 2009 Complete magnetoelectric (ME) phase diagrams of orthorhombic $R$MnO$_{3}$ with and without magnetic moments on the $R$ ions have been established. Three kinds of multiferroic ground states, the $ab$-cycloidal, the $bc$-cycloidal, and the collinear $E ...
Arima, T. +5 more
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source