Results 131 to 140 of about 207,082 (368)

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

Establishment of a biosafe murine model of skeletal tuberculosis using Mycobacterium smegmatis

Animal Models and Experimental Medicine, EarlyView.
This study developed a biosafe, accessible, and versatile murine model of bone TB using Mycobacterium smegmatis, a fast‐growing, nonpathogenic mycobacterial species with high genomic homology to Mycobacterium tuberculosis. Three infection routes—subperiosteal calvarial injection, intratibial injection, and intracardiac (left ventricular) inoculation ...
Yewei Jia, Yuhuai Guo, Yusheng Yang, Jie Zhang, Ziyang Zhang, Ying Qu, Jiulin Tan, Jie Shen, Nathachit Limjunyawong, Jianzhong Xu, Zehua Zhang, Fei Luo, Ce Dou   +12 more
wiley   +1 more source

A6.13 Minor Discrepancy Between BMD of Spine and Hip [PDF]

, 2013
Poran Farahifard, Shahid Sadoughi, Mohammad Bagher Owlia, Shahid Sadoughi   +3 more
openalex   +1 more source

A Novel Transcriptional Slippage Mechanism Rescues Dystrophin Expression from a DMD Frameshift Variant

Annals of Neurology, EarlyView.
Pathogenic DMD variants usually follow the reading‐frame rule: out‐of‐frame changes cause Duchenne muscular dystrophy, whereas in‐frame ones produce Becker muscular dystrophy (BMD). We report a 23‐year‐old man with BMD‐like weakness, calf hypertrophy, elevated creatine kinase, and dilated cardiomyopathy.
Hiroya Naruse, Jun Mitsui, Akatsuki Kubota, So Okubo, Shuichiro Mitsuchi, Kensho Sumi, Shuichi Tanifuji, Shogo Komaki, Asuka Kitamura, Meiko Maeda, Daiki Yashita, Atsushi Sudo, Takashi Matsukawa, Masashi Hamada, Wataru Satake, Shoji Tsuji, Tatsushi Toda   +16 more
wiley   +1 more source

Anti-Osteoporosis Is Imperative in Prevention of Progress of Ankylosing Spondylitis

International Journal of General Medicine
Bin Zheng,* Panfeng Yu,* Haiying Liu, Yan Liang Spine Surgery, Peking University People’s Hospital, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yan Liang, Email liangyan_spine@163 ...
Zheng B, Yu P, Liu H, Liang Y
doaj  

Romosozumab and Denosumab Combination Therapy After Denosumab in Postmenopausal Osteoporosis

Arthritis &Rheumatology, Accepted Article.
Background Transition from long‐term denosumab to PTH‐analogs or romosozumab might expose patients to the risk of the so‐called rebound phenomenon. Adding romosozumab to denosumab might represent an option in patients experiencing a fracture while on denosumab.
Giovanni Adami, Francesco Pollastri, Angelo Fassio, Filippo Montanari, Anna Piccinelli, Camilla Benini, Emma Pasetto, Carmen Dartizio, Davide Gatti, Maurizio Rossini, Ombretta Viapiana   +10 more
wiley   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK pathways

Arthritis &Rheumatology, Accepted Article.
Introduction Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source

Establishing Sitafloxacin Epidemiological Cut-off Values (ECOFFs) for Clinical Bacterial Isolates

Infection and Drug Resistance
Jingjia Zhang,1,2,* Xue Li,1,* Xinmiao Jia,3,* Yun Li,4 Bo Zheng,4 Yunsong Yu,5 Fupin Hu,6 Ziyong Sun,7 Zhongju Chen,7 Ge Zhang,1 Wei Kang,1 Tong Wang,1 Jin Li,1 Haotian Gao,1 Qiaolian Yi,1 Wei Yu,1,8 Xiaobing Chu,1,8 Yingchun Xu,1 Qiwen ...
Zhang J, Li X, Jia X, Li Y, Zheng B, Yu Y, Hu F, Sun Z, Chen Z, Zhang G, Kang W, Wang T, Li J, Gao H, Yi Q, Yu W, Chu X, Xu Y, Yang Q   +18 more
doaj  

A suggested prototype for assessing bone health [PDF]

, 2015
Background- Osteoporosis is becoming a health concern worldwide. Considering the fact that prevention plays an important role in reducing the burden of this silent disease and in view of the limited resources available, many countries have adopted ...
Aghaei Meybodi, H.-D., Bayegi, F., Derakhshan, S., Dini, M., Ebrahimi, M., Etemad, K., Hajian, M., Jouyandeh, Z., Karimi, M., Keshtkar, A., Khashayar, P., Larijani, B., Mohammadi, Z., Nabavi, H., Ramezani, M., Razi, F., Sadigh, H., Saghafi, S.   +17 more
core  

Why We Need to Study Assisted Methods to Teach Typing to Nonspeaking Autistic People

Autism Research, EarlyView.
ABSTRACT At least one third of autistic people have limited or no speech. Most nonspeaking autistic people are never provided alternatives that would enable the full range of expression that speech allows, significantly limiting their access to educational, social, and employment opportunities.
Vikram K. Jaswal, Barry M. Prizant, Morgan D. Barense, Kristie Patten, Gary Stobbe   +4 more
wiley   +1 more source