Results 141 to 150 of about 2,061,437 (333)

E-Government, Trust and Corruption

International Journal of Information Science and Management, 2014
Governments around the worlds especially in developing countries face with tremendous challenges.  High or moderate rate of corruption can be named as one of the most important of these challenges.
Shahram Raeisi Dehkordi, Shahrooz Raeisi Dehkordi   +1 more
doaj  

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

Engineering collagen-based biomaterials for cardiovascular medicine

Collagen and Leather
Cardiovascular diseases have been the leading cause of global mortality and disability. In addition to traditional drug and surgical treatment, more and more studies investigate tissue engineering therapeutic strategies in cardiovascular medicine ...
Xianghao Zuo, Yao Xiao, Jing Yang, Yuanmeng He, Yunxiang He, Kai Liu, Xiaoping Chen, Junling Guo   +7 more
doaj   +1 more source

Subnormothermic Oxygenated Machine Perfusion (24 h) in DCD Kidney Transplantation

Transplantation Direct
Background. Ex vivo kidney perfusion is an evolving platform that demonstrates promise in preserving and rehabilitating the kidney grafts. Despite this, there is little consensus on the optimal perfusion conditions.
Nader Abraham, MBBS, Qimeng Gao, MD, Riley Kahan, MBS, Isaac S. Alderete, BS, Bangchen Wang, MD, PhD, David N. Howell, MD, PhD, Imran J. Anwar, MD, Joseph M. Ladowski, MD, PhD, Kentaro Nakata, MD, Ethan Jarrett, BS, Kendall Hlewicki, BS, Greta Cywinska, BA, Ryan Neill, Charles Aardema, MS, David A. Gerber, MD, Prabir Roy-Chaudhury, MD, Benjamin A. Hughes, PhD, Matthew G. Hartwig, MD, Andrew S. Barbas, MD   +18 more
doaj   +1 more source

Relation between obesity and the oestrogen receptor status of breast cancer [PDF]

, 2014
Introduction: Obesity is a growing problem in the Western world. Correlations have been found between increasing body mass index (BMI) and breast cancer.
Caruana Dingli, Gordon, Paris, Etienne Mark, Pisani, David   +2 more
core  

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Moderators of the effects of exercise and manual therapy for people with knee and hip osteoarthritis: A secondary analysis of the MOA trial

Arthritis Care &Research, Accepted Article.
Objective This study aimed to investigate potential moderators influencing the effects of manual therapy and exercise therapy on pain and functional outcomes in individuals with knee and/or hip osteoarthritis, using data from the MOA trial. Design This is a secondary analysis of data from the MOA trial that compared the clinical effectiveness of manual
Daniel Cury Ribeiro, Sarah E. Lamb, J. Haxby Abbott   +2 more
wiley   +1 more source

Minimal important change and minimal clinically important difference in pain and function with exercise in hip osteoarthritis

Arthritis Care &Research, Accepted Article.
Objective The objective of this study was to estimate the minimal important change (MIC) and minimal clinically important difference (MCID) for pain and physical function in individuals with hip osteoarthritis (OA) following a physiotherapist‐guided exercise intervention.
Yareni Guerrero, Fiona Dobson, Venkatesha Venkatesha, Kim Allison, Gabrielle Knox, Libby Spiers, Travis Haber, David J Hunter, Michelle Hall   +8 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients with Extra‐Renal Systemic Lupus Erythematosus – A Systematic Review & Meta‐analysis

Arthritis Care &Research, Accepted Article.
Background Clinical response to Mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with SLE, particularly those with extra‐renal ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Fingerprints of brain disease: connectome identifiability in Alzheimer’s disease

Communications Biology
Functional connectivity patterns in the human brain, like the friction ridges of a fingerprint, can uniquely identify individuals. Does this “brain fingerprint” remain distinct even during Alzheimer’s disease (AD)?
Sara Stampacchia, Saina Asadi, Szymon Tomczyk, Federica Ribaldi, Max Scheffler, Karl-Olof Lövblad, Michela Pievani, Aïda B. Fall, Maria Giulia Preti, Paul G. Unschuld, Dimitri Van De Ville, Olaf Blanke, Giovanni B. Frisoni, Valentina Garibotto, Enrico Amico   +14 more
doaj   +1 more source