Results 171 to 180 of about 1,628,176 (291)

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Understanding the Impact of Weight on Quality of Life and Willingness to Pay for Obesity Management in the APAC Region. [PDF]

Clin Obes
Ko HJ, Kapoor N, Garcia MM, Jung SG, Romano JGU, Hocking SL.   +5 more
europepmc   +1 more source

Study of Height, Weight and BMI in Type 2 Diabetes Mellitus in Western Maharashtra

, 2012
Sharma Pranjali P, Prasad H.B Prasad H.B
openalex   +1 more source

Author response for "Efficacy and safety of adding sotagliflozin, a dual <scp>SGLT1</scp> and <scp>SGLT2</scp> inhibitor, to optimized insulin therapy in adults with type 1 diabetes and baseline <scp>BMI</scp> ≥27 kg/m ²"

, 2020
Thomas Danne, Steven V. Edelman, Juan P. Frías, Francisco Javier Ampudia‐Blasco, Philip Banks, Wenjun Jiang, Michael J. Davies, Sangeeta Sawhney   +7 more
openalex   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

The role of obesity and Type 2 diabetes in lung health: A systematic review (2024). [PDF]

PLoS One
Lecky R, Grogan S, Shukla P, Atkinson S, McClean PL, Kelly C.   +5 more
europepmc   +1 more source

A Cross-Sectional Study to Find the Correlation Between Age and BMI with Bone Mineral Density in Pre and Post-Menopausal Women

Ankita Juyal
openalex   +1 more source

Is body obesity related to osteoporosis in normal-BMI older adults?

, 2017
Wing P. Chan, Yi-Chien Lu, Ying Lin, Poon‐Ung Chieng   +3 more
openalex   +1 more source

Ultra sonographic study of right lobe of liver morphometry with age, sex, height, weight and BMI of individual in central Indian population

, 2022
Anand Kumar Mishra, Shema Nair, Naresh Thaduri, Neha Rai, S D Gupta, Vikas Pandey   +5 more
openalex   +2 more sources

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

Advanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu, Yunyuan Yu, Guangrong Yin, Huiqun Hu, Shishuo Li, Yuting Tang, Yimin Liu, Maoyuan Li, Liang liang Wang, Chao Xu, Gongyin Zhao, Baojun Zhou, Yuji Wang   +12 more
wiley   +1 more source