Results 201 to 210 of about 1,628,176 (291)

Synovial Fluid‐derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP‐1 Signaling Pathway

Advanced Science, EarlyView.
Traditionally considered sterile, the articular cavity is now recognized to harbor microbial communities influencing osteoarthritis (OA). Integrating 16S rRNA sequencing and culturomics, Micrococcus luteus is enriched in advanced OA. Notably, M. luteus G18 exacerbates cartilage degeneration via TLR2/JNK/AP‐1‐mediated ECM disruption, revealing intra ...
Tingtao Chen, Qingwei Zeng, Tangchang Xu, Xinyue Qi, Kaiyi Li, Jing Wei, Liang Hao   +6 more
wiley   +1 more source

Lifecourse genome-wide association study meta-analysis refines the critical life stages for adiposity's influence on breast cancer risk. [PDF]

Sci Adv
Power GM, Bhatta L, Hughes AM, Medina-Gomez C, Richmond A, Leyden G, Lloyd-Lewis B, Sanderson E, Richmond R, Corfield EC, McCartney D, Hayward C, Fontes Marques I, Rivadeneira F, Åsvold BO, Hemani G, Felix JF, Brumpton B, Havdahl A, Davey Smith G.   +19 more
europepmc   +1 more source

Effects of pre-pregnancy BMI and gestational weight gain on pregnancy and neonatal outcomes in Poland [PDF]

Justyna Marchewka, Joanna Nieczuja-Dwojacka, Krystyna Krygowska, В И Богданович, Dorota Sys, Barbara Baranowska, Magdalena Kobus   +6 more
openalex   +1 more source

COMPARISON OF CORE MUSCLE STRENGTH IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND IN AGE, GENDER AND BMI MATCHED HEALTHY INDIVIDUALS [PDF]

, 2017
Priya Deshmukh, Rachna Arora
openalex   +1 more source

Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early‐Onset Colorectal Cancer

Advanced Science, EarlyView.
This study identifies a unique physical signature of colorectal cancer in younger adults: their tissues are mechanically stiffer than those in older patients with the same cancer. Furthermore, stromal remodeling in early‐onset colorectal cancer promotes epithelial mechanotransduction and proliferation, showing how mechanical alterations in the tissue ...
Nicole C. Huning, Munir H. Buhaya, Victor V. Nguyen, Afeefah Khazi‐Syed, Haider A. Ali, Adil Khan, Angela Fan, Robert C. Fisher, Zhikai Chi, Indu Raman, Guangchun Chen, Chengsong Zhu, Mengxi Yu, Andrew R. Jamieson, Sara Roccabianca, Victor D. Varner, Cheryl M. Lewis, Emina H. Huang, Jacopo Ferruzzi   +18 more
wiley   +1 more source

The U-shaped Association between Body Mass Index (BMI) and Cognitive Impairment: Associated Characteristics in Low BMI and High BMI Chinese Adults. [PDF]

Diabetes Metab J
Chang Y, Wu F, Han F, Yi X.
europepmc   +1 more source

52 – An evaluation of a 5-week, school-based, exergaming intervention using the Gamercize Power Stepper on BMI and physical activity during school lunch breaks in British primary-school children [PDF]

, 2012
Michael Duncan, Stephen Birch, Lorayne Woodfield, Joanne Hankey   +3 more
openalex   +1 more source

Targeting the CMKLR1‐Mediated Signaling Rebalances Immunometabolism State in Middle‐Age Testicular Macrophages

Advanced Science, EarlyView.
In middle age, testicular CMKLR1⁺ macrophages exhibited a pro‐inflammatory immunometabolic profile, mediated by adipose signals associated with high BMI. However, inhibition of CMKLR1 signaling, either through Cmklr1 genetic ablation or treatment with a CMKLR1 antagonist peptide, can reverse this phenotype.
Zhendong Zhu, Feifei Du, Yang Liu, Jinchunzi Yang, Lei Ge, Tianxia Xiao, Mengxia Li, Jie Chen, Jia Tang, Yali Yang, Jian V. Zhang   +10 more
wiley   +1 more source

Correlation of triglyceride glucose-body mass index, bedside index for severity in acute pancreatitis, and C-reactive protein-to-lymphocyte ratio with disease severity in patients with hyperlipidemic acute pancreatitis: A retrospective-cohort study. [PDF]

J Int Med Res
Xie R, Zhang Y.
europepmc   +1 more source

Development of standard shoe-lasts that reflect BMI and foot characteristics of senior generation women [PDF]

, 2017
Woong-Sub Lee, Sunah Kim
openalex   +1 more source