Results 131 to 140 of about 9,553,512 (310)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Unveiling the corporate governance dynamics: exploring the nexus of board composition, audit committee attributes, foreign ownership, and firm performance in an emerging market

open access: yesCogent Business & Management
This study investigates the collective impact of key corporate governance variables namely board composition, audit committee characteristics, and foreign ownership on firm performance in an emerging economy, India.
Mohd Arsh   +5 more
doaj   +1 more source

Columbia Accident Investigation Board Report: Volume 5. Other Significant Documents

open access: yes, 2003
Fifth volume of the final report produced by the Columbia Accident Investigation Board including documents produced by NASA and other organizations that were provided to the Columbia Accident Investigation Board in support of its inquiry into the ...
Columbia Accident Investigation Board
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Board characteristics and sustainability report quality: Profitability as a moderating variable

open access: yesJournal of Accounting and Investment
Research aims: This research aims to determine the influence of board characteristics on the quality of sustainability reports and examine the role of profitability as a moderating variable in manufacturing companies in Indonesia.
Marfuah Marfuah   +1 more
doaj   +1 more source

Columbia Accident Investigation Board Report: Volume 4. Other Technical Documents

open access: yes, 2003
Fourth volume of the final report produced by the Columbia Accident Investigation Board including documents produced by NASA and other organizations which were provided to the Columbia Accident Investigation Board in support of its inquiry into the ...
Columbia Accident Investigation Board
core  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

IMPACT OF BOARD CHARACTERISTICS ON FINANCIAL PERFORMANCE OF LISTED INDUSTRIAL GOODS FIRMS IN NIGERIA

open access: yesGusau Journal of Accounting and Finance
This study investigates the impact of board characteristics on financial performance of listed industrial goods firms in Nigeria. The population of the study consist of all the twelve (12) listed industrial goods firms in Nigeria.
Muhammad Usaini   +2 more
doaj   +1 more source

Minutes of the meeting of the Western Health Board 3rd December 1984

open access: yes, 1985
Minutes of the regular Western Health Board meetings, held in ...
Western Health Board (WHB)
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy