Results 181 to 190 of about 9,553,512 (310)
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Agenda Book, Meeting of the Board of Visitors, February, 2015
, 2015 The Board of Visitors Agenda Book from the February 2015 meeting. The book includes Committee Meeting Schedule, Alumni Relations, Audit and Compliance, Athletics, Academic Affairs, Student Affairs, Administration, Buildings & Grounds ...
College of William and Mary. Board of Visitors
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FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Katherine Hospital Management Board Annual Report 1997/98
, 1998 Please find attached the 1997 /98 Annual Report of the Katherine Hospital Management Board, in accordance with Section 25 ( 1) of the Hospital Management Board Act.
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Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
THE INFLUENCE OF BOARD CHARACTERISTICS ON SUSTAINABILITY
Journal of Contemporary Issues and Thought, 2017 Mohamad Iruwan Ghuslan +1 more
openaire +2 more sources
Annual report / Katherine Hospital Management Board 1997/98
, 1998 Please find attached the 1997 /98 Annual Report of the Katherine Hospital Management Board, in accordance with Section 25 ( 1) of the Hospital Management Board ...
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Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Gender differences among board-certified general surgeons in Israel: demographics, professional advancement, and leadership. [PDF]
Isr J Health Policy ResEliyahu S, Hershkovitz Y, Shapira OY.
europepmc +1 more source