Results 111 to 120 of about 3,962,600 (348)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Gender Diversity and Firm Performance: Evidence from Dutch and Danish Boardrooms [PDF]
Drawing on the business case for gender diversity, this article examines whether board gender diversity has a positive effect on firm performance, based on evidence from the Netherlands and Denmark.
Chantal Remery +2 more
core
A survey of the marine environment near the city of Watsonville ocean outfall [PDF]
, 1972 The California Department of Fish and Game and the State Water Resources Control Board (through Regional Board #3, Central Coast) entered into an agreement whereby Department biologist-divers conducted a subtidal ecological investigation of the marine ...
Odenweller, Dan B.
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A Seat at the Table: An Examination of Hospital Governing Board Diversity, 2011-2021. [PDF]
J Healthc Manag, 2023 Silvera GA, Erwin CO, Garman AN.
europepmc +1 more source
Balance rather than critical mass or tokenism: gender diversity, leadership and performance in financial firms [PDF]
, 2019 Purpose: This study analyzes how board’s gender diversity, and more specifically a gender-balanced configuration—i.e., a proportion of women in the boardroom ranging between 40% and 60%—affects economic and risk oriented performance in financial firms ...
Lafuente González, Esteban Miguel +1 more
core +2 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Board Diversity: Moving the Field Forward [PDF]
Corporate Governance: An International Review, 2015 Adams, Renee B. +3 more
openaire +2 more sources
Meaning and Impact of Board and Staff Diversity in the Philanthropic Field: Findings from a National Study [PDF]
, 2002 The report's premise is that the staffs and boards of philanthropic institutions have not kept pace with the general population in terms of diversity, and that if responsiveness and diversity are linked, then foundations must attend to their internal ...
Aileen Shaw +4 more
core
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source