Results 161 to 170 of about 139,723 (310)

Independent boards

External Scientific and Advisory Committee ESAC and Data and Safety Monitoring Board DSMB A report on the constitution of the ESAC and Independent DSMB will be prepared ...
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Independence Standards Board - Minutes, Meeting of November 19, 1999: Public Session

, 1999
https://egrove.olemiss.edu/aicpa_assoc/1640/thumbnail ...
Independence Standards Board
core  

Correction: The moderation role of board independence change in the relationship between board characteristics, related party transactions, and financial performance. [PDF]

PLoS One
Almaqtari FA, Farhan NHS, Al-Hattami HM, Elsheikh T.   +3 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Independence Standards Board - Minutes of Meetings, Meeting of Public Meeting, October 20, 1997

, 1997
https://egrove.olemiss.edu/aicpa_assoc/1632/thumbnail ...
Independence Standards Board
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Board Characteristics and Corporate Performance in the Netherlands [PDF]

We analyze the performance-board characteristic nexus of Dutch listed firms. The Netherlands has a continental-European two-tier board structure. This makes it interesting to analyze the impact of management and supervisory board characteristics (size ...
Theo J.B.M. Postma, Hans van Ees, Elmer Sterken   +2 more
core  

Improvement in activities of daily living in postoperative patients with cervical spondylotic myelopathy undergoing intensive rehabilitation in a convalescent rehabilitation ward: A retrospective observational study. [PDF]

Medicine (Baltimore)
Sasaki S, Saito W, Nakazawa T, Kamide N, Maeda T, Kobayashi A, Miyazaki M, Nakazono T, Mihira R, Imura T, Miyagi M, Masaki Y, Kenmoku T, Fukuda M, Inoue G, Takaso M.   +15 more
europepmc   +1 more source