Results 201 to 210 of about 1,546,729 (266)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Adjunctive Maneuvers for Glottic Entry During Pediatric Nasotracheal Intubation: A Prospective Observational Cohort Study. [PDF]

J Clin Med
Tong Y, Du J, Guo H, Wei R, Liu W, Liu H.   +5 more
europepmc   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Adoption and challenges of the 2018 International Society for Heart and Lung Transplantation consensus statement on adult and pediatric airway complications grading system in lung transplantation: A multicenter survey. [PDF]

JHLT Open
Crespo MM, Solé A, Bermudez CA, Richards TJ, Mazur Z, Budev M.   +5 more
europepmc   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Cardiology knowledge assessment of retrieval-augmented open versus proprietary large language models. [PDF]

PLOS Digit Health
Tarabanis C, Khurshid S, Karamanou A, Piperaki R, Mavromatis LA, Hatzimemos A, Tachmatzidis D, Bakogiannis C, Vassilikos V, Ellinor PT, Jankelson L, Kalampokis E.   +11 more
europepmc   +1 more source

i-Factor™ Bone Graft Versus Demineralized Bone Matrix for Single-Level Anterior Cervical Discectomy and Fusion: A Propensity Score-Matched Analysis. [PDF]

J Clin Med
Kim DH, Hur JW, Kim JY, Hong JT.
europepmc   +1 more source

Local Ablative Therapy in Breast Cancer Liver Metastases: Survival Outcomes and Prognostic Factors-A Single-Center Retrospective Study. [PDF]

J Clin Med
Sertesen Çamöz E, Bayrak A, Karaçin C, Törenek Ş, Deliktaş Onur İ, Önder T, Ateş Ö.   +6 more
europepmc   +1 more source

Education Research: The Future of Child Neurology Residency Training: The Perspective of a Child Neurology Society Task Force. [PDF]

Neurol Educ
Cohen BH, Gilbert DL, Xixis K, Banwell BL, Singh A, Pagano LM, Brooks-Kayal A, Kirkpatrick L, Schor NF, Mar SS, Crowder D, Terrell M, Kang PB.   +12 more
europepmc   +1 more source