Results 1 to 10 of about 4,781 (204)

Increased intervals in enzyme replacement therapy for stable type 1 Gaucher disease: A non-inferiority sequential trial emulation. [PDF]

J Intern Med
Abstract Objective To compare the efficacy and safety of extended interval (Q3–4W) enzyme replacement therapy (ERT) versus standard biweekly (Q2W) ERT in clinically stable type 1 Gaucher disease (GD) patients. Methods We emulated a target trial with a sequential trial design, using data from the French Gaucher Disease Registry.
Beydon M, Stirnemann J, Yousfi K, Zebiche S, Hamroun D, Brassier A, Pichard S, Swiader L, de Villemeur TB, Héron B, Dalbies F, Cador B, Guemann AS, Gaches F, Hivert B, Leguy-Seguin V, Masseau A, Pers YM, Pettazzoni M, Bekri S, Caillaud C, Guillou EL, Szymanowski M, Astudillo L, Mauhin W, Nadjar Y, Serratrice C, Berger MG, Camou F, Belmatoug N, Nguyen Y, French Evaluation of Gaucher Disease Treatment Committee.   +31 more
europepmc   +2 more sources

Transformation des structures agricoles et recomposition des paysages de bocage

Projets De Paysage, 2015
In the region of Basse-Normandie, the process of “agricultural modernisation” started in the 1950s has led to an unprecedented reorganisation of rural spaces and landscapes.
Daniel Delahaye
exaly   +3 more sources

Shedding light on the parasite communities and diet of the deep-sea shark Deania profundorum (Smith & Radcliffe, 1912) (Squaliform: Centrophoridae) from the Avilés Canyon (southern Bay of Biscay). [PDF]

J Fish Biol
Abstract Deep‐sea elasmobranchs are less resilient to the increasing scale of anthropogenic impacts such as fisheries, owing to their life‐history traits. The necessity for proper management measures is hampered by the scant knowledge on these taxa and their biology. Here we provide the first comprehensive insight into the parasite infracommunities and
Isbert W, Rodríguez-Cabello C, Montero FE, Carrassón M, Frutos I, Pérez-Del-Olmo A.   +5 more
europepmc   +2 more sources

Pulmonary artery resection with autologous pericardial conduit to avoid pneumonectomy in lung neoplasms surgery: How to do itCentral Message [PDF]

JTCVS Techniques, 2023
Leslie Madelaine, MD, Alain Bernard, MD, PhD, Halim Abou Hanna, MD, Aurélien Moret, MD, Pierre-Benoit Pagès, MD, PhD   +4 more
doaj   +2 more sources

Epidemiology of Gaucher Disease in France: Trends in Incidence, Mortality, Management, and Complications Over Three Decades. [PDF]

J Inherit Metab Dis
ABSTRACT Gaucher disease (GD) is a rare autosomal‐recessive lysosomal disorder caused by glucocerebrosidase deficiency. In this study, we described the epidemiology of GD in France over more than three decades. The French GD registry (FGDR) includes all known patients with GD in France.
Nguyen Y, Beydon M, Yousfi K, Zebiche S, Hamroun D, Brassier A, Pichard S, Swiader L, Billette de Villemeur T, Héron B, Dalbies F, Cador B, Guemann AS, Gaches F, Hivert B, Leguy-Seguin V, Masseau A, Deshayes R, Pers YM, Pettazzoni M, Bekri S, Caillaud C, Le Guillou E, Szymanowski M, Astudillo L, Mauhin W, Nadjar Y, Serratrice C, Berger MG, Camou F, Belmatoug N, Stirnemann J, French Evaluation of Gaucher Disease Treatment Committee.   +32 more
europepmc   +2 more sources

Retour d'expérience - Le programme Breizh Bocage au service de la restauration de l'eau [PDF]

Sciences, Eaux & Territoires, 2019
La Bretagne, très tôt confrontée à une vulnérabilité pour assurer son alimentation en eau potable, a développé des approches territoriales innovantes pour limiter les phénomènes de dégradation de la qualité des milieux.
P. RENAULT
doaj   +2 more sources

La trajectoire paysagère d’un bassin versant bocager normand depuis deux siècles : enjeux méthodologiques pour une étude géohistorique

Cybergeo, 2023
The bocage landscape of north-western France has undergone major changes since the middle of the twentieth century, its structure having been altered by land consolidation, the rationalization and enlargement of plots, and the levelling of hedgerows. The
Mathilde Guillemois, Daniel Delahaye, Romain Reulier   +2 more
doaj   +1 more source

Caractériser et suivre qualitativement et quantitativement les haies et le bocage en France [PDF]

Sciences, Eaux & Territoires, 2019
Patrimoine historique et culturel, les bocages connaissent un recul depuis de nombreuses années. La mécanisation de l'agriculture et l'abandon des modes de culture traditionnels ont abouti à l'arrachage d'un grand nombre de haies.
S. MORIN, L. COMMAGNAC, F. BENEST
doaj   +2 more sources

Teurtheville-Bocage [PDF]

ADLFI. Archéologie de la France - Informations, 2007
Date de l'operation : 2007 (SD) Inventeur(s) : Jeanne Laurence (BEN) ; Duclos Caroline ; Le Gaillard Ludovic (INRAP) ; Paez-Rezende Laurent (INRAP) L’occupation antique du Pas du Vivray (bois de Barnavast) a ete inventoriee, en 1828, par Charles de Gerville, sous le terme generique de « site a tegulae ». La decouverte d’abondants rates de cuisson, puis
Laurence Jeanne, Caroline Duclos, Ludovic Le Gaillard, Laurent Paez-Rezende   +3 more
openaire   +1 more source

Increased VLDL-apoB and IDL-apoB production rates in nonlipodystrophic HIV-infected patients on a protease inhibitor-containing regimen

Journal of Lipid Research, 2003
The aim of this study was to identify the first abnormalities of apolipoprotein B (apoB) metabolism in HIV-infected patients treated by antiretroviral therapy (ART) with protease inhibitors (PIs).
Jean Michel Petit, Michel Duong, Emmanuel Florentin, Laurence Duvillard, Pascal Chavanet, Jean Marcel Brun, Henri Portier, Philippe Gambert, Bruno Vergès   +8 more
doaj   +1 more source