An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Non-ablative transurethral laser treatment for collagen remodeling with functional recovery in an in vivo model of stress urinary incontinence. [PDF]
Shin H, Ta MD, Kang M, Lee Y, Kang HW.
europepmc +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
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Predicting Prostatic Obstruction and Bladder Outlet Dysfunction in Men with Lower Urinary Tract Symptoms and Small-to-Moderate Prostate Volume Using Noninvasive Diagnostic Tools. [PDF]
Tian JH, Hsieh TC, Kuo HC.
europepmc +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Serum long noncoding RNA FAM83H-AS1 serves as a potential noninvasive diagnostic biomarker for ovarian cancer. [PDF]
Tian C +6 more
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Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
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Patient Experience and Perception of First Language Usage in Healthcare: The Welsh Perspective. [PDF]
Edwards ME +6 more
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Evaluation of Habitat Suitability and Assessment of the Invasion Risk of Water Hyacinth [<i>Eichhornia crassipes</i> (Mart.) Solms] in Global Freshwater Ecosystems. [PDF]
Adhikari P +4 more
europepmc +1 more source

