Results 51 to 60 of about 24,773 (245)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Re-storing the Earth: A Phenomenological Study of Living Sustainably

open access: yesPhenomenology & Practice, 2013
Living sustainably evokes ideas of lived, bodily engagement with and perception of the earth. Yet, modern ways of thinking and speaking have slowly alienated the earth from consciousness. Using phenomenological methods, the author examines the experience
Jessica Buckley
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

On the (Painterly) Interruption of Projected Images: Bodily Engagement as Discontinuous Transition [PDF]

open access: yes, 2014
This practice-based project considers what happens when projected video/film is placed in combination with drawing, and vice versa. The research conceives of the staging of video projection installations and related works in terms of their spatial and temporal dimensions.
openaire   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Gymnastic play as movement-based learning to enhance bodily–kinesthetic intelligence in early childhood

open access: yesJournal of Childhood and Elementary Studies
Background: Bodily–kinesthetic intelligence is an essential component of early childhood development, closely related to children’s ability to control body movements, coordinate muscles, and express ideas through physical activity.
Nilawati Tajuddin, Silvi Indriani
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Reading out bodily cues to predict interactions

open access: yesScientific Reports
Successful motor coordination in social interactions requires the rapid interpretation of others’ intentions from their actions. Previous research suggests that individuals use early bodily cues, such as movement kinematics and gaze, to predict others ...
Edoardo Arcuri   +2 more
doaj   +1 more source

Applied Art: Innovative Thinking From a Material Perspective

open access: yesInFormation: Nordic Journal of Art and Research, 2013
The modern world is continuously engaged in a racing processes aimed towards building a favourable future society. In this development, the apparent tools seem to be related to theoretical thought, new technology, avant-garde approaches and innovation ...
Anneli Hoel Fjærli, Ida Haugland
doaj   +1 more source

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