Results 101 to 110 of about 3,274,950 (328)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Transmission Delay of Multi-hop Heterogeneous Networks for Medical Applications

, 2012
Nowadays, with increase in ageing population, Health care market keeps growing. There is a need for monitoring of Health issues. Body Area Network consists of wireless sensors attached on or inside human body for monitoring vital Health related problems ...
Israr, I., Javaid, N., Khan, M. A., Khan, Z. A., Qasim, U., Yaqoob, M. M.   +5 more
core   +1 more source

Whole-body averaged specific absorption rate estimation using a personal, distributed exposimeter [PDF]

, 2015
For the first time, a body area network (BAN) is used to construct a personal, distributed exposimeter (PDE), which can measure the whole-body averaged specific absorption rate (SAR(wb)) in real life, together with the incident power density (S-inc). The
Agneessens, Sam, Joseph, Wout, Martens, Luc, Rogier, Hendrik, Thielens, Arno, Van Torre, Patrick, Vanveerdeghem, Peter, Vermeeren, Günter   +7 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Measuring Fatigue of Soldiers in Wireless Body Area Sensor Networks

, 2013
Wireless Body Area Sensor Networks (WBASNs) consist of on-body or in-body sensors placed on human body for health monitoring. Energy conservation of these sensors, while guaranteeing a required level of performance, is a challenging task.
Faisal, S., Javaid, N., Khan, Z. A., Nayab, D., Zahid, M.   +4 more
core   +1 more source

Identification key scheme to enhance network performance in wireless body area network

Periodicals of Engineering and Natural Sciences (PEN), 2019
Wireless Body Area Network (WBAN) refers to a group of small intelligent electronic devices placed on the human body to monitor its vital signals.
Israa Albaeazanchi, Haider Rasheed Abdulshaheed, Shihab A. Shawkat, Siti Rahayu Binti Selamat   +3 more
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Generalized Activity Assessment computed fully distributed within a Wireless Body Area Network [PDF]

, 2016
Currently available wearables are usually based on a single sensor node with integrated capabilities for classifying different activities. The next generation of cooperative wearables could be able to identify not only activities, but also to evaluate
Seiffert, Martin, Holstein, Flavio, Schiller, Jochen, Schlosser, Rainer   +3 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source