Results 71 to 80 of about 2,049,351 (289)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Standardization for Body Area Networks

open access: yesIEICE Transactions on Communications, 2009
Body Area Networks (BAN) can provide a wide range of applications including medical support, healthcare monitoring, and consumer electronics with increased convenience or comfort. To harmonize with the strong demands from both medical and healthcare societies, and information and communications technology (ICT) industries, IEEE 802.15.6 task group (TG6)
Arthur W. ASTRIN   +2 more
openaire   +2 more sources

A truncated conical dielectric resonator antenna for body-area network applications [PDF]

open access: yes, 2009
Copyright © 2009 IEEEAn inverted truncated annular conical dielectric resonator antenna (DRA) for potential use in body-area network (BAN) applications is introduced.
Christophe Fumeaux   +4 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

The AmICriM Project: A Truly Body Area Network Application [PDF]

open access: yes, 2008
http://www.emse.fr/~picard/publications/garcia08amicrim.pdfInternational audienceThe major aim of this work is to present the AmICriM (Ambient Intelligence for Crisis Management) current activities as an upcoming research challenge in the area of body ...
Garcia Ruiz, José Esteban   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Multiobjective, Lion Mating Optimization Inspired Routing Protocol for Wireless Body Area Sensor Network Based Healthcare Applications

open access: yesSensors, 2019
The importance of body area sensor networks (BASNs) is increasing day by day because of their increasing use in Internet of things (IoT)-enabled healthcare application services.
Muhammad Faheem   +6 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Approximating Mexican highways with slime mould

open access: yes, 2010
Plasmodium of Physarum polycephalum is a single cell visible by unaided eye. During its foraging behavior the cell spans spatially distributed sources of nutrients with a protoplasmic network. Geometrical structure of the protoplasmic networks allows the
A Adamatzky   +33 more
core   +1 more source

Button Antenna on Textiles for Wireless Local Area Network On Body Applications [PDF]

open access: yes, 2010
A design of a wearable antenna for wireless local area network (WLAN) applications is presented in this study. The antenna consists of a button shape outer cylindrical structure and an internal central via connected to a top disc at one end and the ...
Batchelor, John C.   +2 more
core   +1 more source

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