Results 41 to 50 of about 7,022 (285)

Ballistic performance of a lightweight nacre-inspired armour panel – a numerical study

Composites Part C: Open Access, 2022
This paper provides a numerical investigation on the ballistic performance of ceramic composite armour panels with porous architectures inspired by nacre from mollusc shells.
Abdallah Ghazlan, Tuan Ngo, Ping Tan, Phuong Tran, Keivan Nazari, Yi Min Xie   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An evaluation of the hypodermic needle threat against body armour [PDF]

, 2004
Previous work has addressed protection against stab attacks [1, 2], and slash attacks [3, 4] this has resulted in body armour that is suitable for protecting the torso against knives. Whilst this armour combats the primary lethal injuries to the torso it
Luk, Edwina, Horsfall, Ian, Watson, Celia H.   +2 more
core  

Bioinspired design of flexible armor based on chiton scales

Nature Communications, 2019
Biology has often served as the inspiration for the design of body armor; one common limitation is the flexibility of the resultant armor. Here, the authors examine the armour of chiton and use the observed design principles to 3D print flexible armor.
Matthew Connors, Ting Yang, Ahmed Hosny, Zhifei Deng, Fatemeh Yazdandoost, Hajar Massaadi, Douglas Eernisse, Reza Mirzaeifar, Mason N. Dean, James C. Weaver, Christine Ortiz, Ling Li   +11 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A comparison of the behind armour blunt trauma effects between ceramic faced and soft body armours caused by ballistic impact [PDF]

, 2002
Recently published research has characterised the behind armour blunt trauma (BABT) effects associated with high velocity ballistic impact on textile-based armour faced with a ceramic plate. Subsequently dynamic displacements, accelerations and pressures
Lewis, E. A., Horsfall, Ian, Watson, Celia H.   +2 more
core  

Fish Scale-Inspired Stab-Resistant Body Armour

Materials Proceedings
While commercially available lightweight “stab-proof” apparel exists, it offers little resistance to true stabbing as it is primarily designed to withstand slash attacks. Yet, crimes involving the use of a knife or sharp instrument have consistently been
Sidharath Sharma, Parvez Alam
doaj   +1 more source

The effects of body armour on mobility and postural control of police officers [PDF]

Journal of Bodywork and Movement Therapies, 2020
Police officer use of Individual Light Armour Vests (ILAVs) is increasing due to potential occupational hazards that include blunt trauma, stabbing, and light calibre bullets. It is unclear how addition of this extra load will affect the officer's mobility or postural control.The aim of this study was to determine the effects of various ILAVs on the ...
Ben, Schram, Robin, Orr, Ben, Hinton, Geoff, Norris, Rodney, Pope   +4 more
openaire   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source