Results 91 to 100 of about 2,716,533 (303)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The Production and Body Composition of Kacang Goat Fed Different Quality of Diets [PDF]

, 2013
An experimental study was carried out to assess the effect of diet quality on productivity and bodycomposition of Kacang goat. Fifteen male Kacang goats weighing 14.28 ± 3.36 kg (CV = 23.55%) weredivided into 5 groups based on body weight.
Purnomoadi, A. (A), Restitrisnani, V. (V), Rianto, E. (E)   +2 more
core  

Pre-pregnancy overweight or obesity and gestational diabetes as predictors of body composition in offspring twenty years later : evidence from two birth cohort studies [PDF]

, 2017
Background. Global prevalence of overweight/obesity and gestational diabetes (GDM) is increasing. In pregnant women both conditions affect offspring's later health.
Andersson, S., Eriksson Johan, G., Heinonen, K., Järvelin, M.-R., Kajantie, E., Kaseva, N., Lano, A., Matinolli, H.-M., Raikkonen, K., Sipola-Leppänen, M., Tikanmäki, M., Vääräsmäki, M., Wolke, Dieter   +12 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Effects of Title IX and Sports Participation on Girls' Physical Ability and Weight [PDF]

, 2007
Summarizes findings from "Effects of Title IX and Sports Participation on Girls' Physical Ability and Weight," a study of how legislation to increase girls' participation in sports affected physical activity levels, body mass index, and body ...
Deanna Lewis, Robert Kaestner, Xin Xu
core  

The Extra Load Index as a method for comparing the relative economy of load carriage systems [PDF]

, 2010
The Extra Load Index (ELI) has been proposed as a suitable method of assessing the relative economy of load carriage systems. The purpose of this study was to determine, based on empirical evidence, that the ELI can accommodate variations in both body ...
Cooke, Carlton, Davies, Simeon, Hind, Karen, Lloyd, Ray, Parr, Bridget   +4 more
core   +4 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Higher rating of perceived exertion and lower perceived recovery following a graded exercise test during menses compared to non-bleeding days in untrained females

Frontiers in Physiology
The underrepresentation of the female population in exercise sciences could be attributed, at least in part, to difficulty in appropriately accounting for the effects of the menstrual cycle (MC).
Morgan Delp, Grant A. Chesbro, Brian A. Pribble, Ryan M. Miller, Hugo M. Pereira, Christopher D. Black, Rebecca D. Larson   +6 more
doaj   +1 more source

Reduced sleep duration affects body composition, dietary intake and quality of life in obese subjects. [PDF]

, 2016
Purpose Sleep duration has emerged as a crucial factor affecting body weight and feeding behaviour. The aim of our study was to explore the relationship among sleep duration, body composition, dietary intake, and quality of life (QoL) in obese ...
DI LAZZARO, Luca, Donini, Lorenzo Maria, Federica, Luisi, Giampaolo, Polidoro, Gnessi, Lucio, Lenzi, Andrea, Lubrano, Carla, Mariani, Stefania, Marocco, Chiara, Merola, Gianluca, Poggiogalle, Eleonora, Silvia, Migliaccio   +11 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source