Results 61 to 70 of about 7,095,749 (253)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Condition and energy allocation during the reproductive cycle of the Patagonian redfish Sebastes oculatus from the Argentine continental shelf

Marine and Fishery Sciences
The Patagonian redfish (Sebastes oculatus Valenciennes 1833) is a viviparous species inhabiting the mid and outer shelf waters, as well as the rocky reefs along the Patagonian coast of Argentina.
Karina A. Rodrigues, Ezequiel Leonarduzzi, María I. Militelli, Gustavo J. Macchi   +3 more
doaj   +1 more source

A Case of Letting the Cat out of The Bag—Why Trap-Neuter-Return Is Not an Ethical Solution for Stray Cat (Felis catus) Management

Animals, 2019
Trap-Neuter-Return (TNR) programs, in which stray cats are captured, neutered and returned to the environment are advocated as a humane, ethical alternative to euthanasia.
Heather M. Crawford, Michael C. Calver, Patricia A. Fleming   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The impact of a volcanic ash fall event on the Critically Endangered Barbados leaf-toed gecko Phyllodactylus pulcher

Oryx
Ecosystem disturbance is known to negatively affect herpetofauna. There are, however, few studies on the impact of volcanic ash fallout on reptile species and no known publications on any impacts on the family Phyllodactylidae.
Dennis Connor Blades, Isabel Maria Vique Bosquet   +1 more
doaj   +1 more source

Differences in productive robustness in rabbits selected for reproductive longevity or litter size

Animal, 2009
The aim of this work was to evaluate the ability of a line selected for reproductive longevity (LP) to confront productive challenges compared to a line selected during 31 generations for litter size at weaning (V).
P. Theilgaard, M. Baselga, E. Blas, N.C. Friggens, C. Cervera, J.J. Pascual   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Relationships between individual behaviour and morphometry under different experimental conditions of temperature and feeding in glass eels (Anguilla anguilla) [PDF]

Knowledge and Management of Aquatic Ecosystems, 2008
After Anguilla anguilla larvae reach the European coast, metamorphosing glass eels exhibit an estuarine migration phase and can potentially colonize the continental area.
A. Bardonnet, J. Labonne, J. Laffite, J. Garnier   +3 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source