Results 151 to 160 of about 5,700,279 (369)

Piecewise linear constitutive relations for stretch-limited elastic strings [PDF]

open access: yesarXiv
This study proposes a simple and novel class of stretch-limiting constitutive relations for perfectly flexible elastic strings drawing from modern advances in constitutive theory for elastic bodies. We investigate strings governed by constitutive relations where stretch is a bounded, piecewise linear function of tension, extending beyond the ...
arxiv  

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Politics and the Internet: A Phenomenological Critique [PDF]

open access: yes, 2011
“Politics and the Internet” is a critique of the political potential of the internet from the perspective of Husserl’s discussion of intersubjectivity and objectivity in Cartesian Meditations and Origins of Geometry.
Gregory Cameron
core  

A mathematical justification for nonlinear constitutive relations between stress and linearized strain [PDF]

open access: yesarXiv
We present an asymptotic framework that rigorously generates nonlinear constitutive relations between stress and linearized strain for elastic bodies. Each of these relations arises as the leading order relationship satisfied by a one-parameter family of nonlinear constitutive relations between stress and nonlinear strain.
arxiv  

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Correlation between Tibetan and traditional Chinese medicine body constitutions: A cross-sectional study of Tibetan college students in the Tibet Autonomous Region

open access: yesJournal of Traditional Chinese Medical Sciences, 2018
Objective: To evaluate the correlation between the body constitution types of Tibetan medicine and traditional Chinese medicine (TCM). Methods: The cluster sampling method was employed to recruit participants from a university in the Tibet Autonomous ...
Hui Luo   +3 more
doaj  

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Democratic constitution-making bodies: The perils of a partisan convention [PDF]

open access: yesInternational Journal of Constitutional Law, 2018
Constituent conventions have traditionally occupied a privileged position within normative theories of constitution-making. It is claimed that compared to a constituent legislature, an assembly specially commissioned to write a constitution is better able to reflect citizens' preferences and promote an impartial constitutional design.
openaire   +3 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy