Results 171 to 180 of about 5,700,279 (369)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Annotated Constitution of the State of Rhode Island and Providence Plantations [PDF]

open access: yes, 1988
The convention staff has here prepared an annotated version of the new Constitution which compares the new document with the 1843 Constitution, noting the similarities and differences and providing some commentary on those sections that have been added ...

core   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

El guardián de la Constitución en la obra de E. Sieyès: un precedente de la Justicia Constitucional en Europa

open access: yesRevista Vasca de Administración Pública, 2014
This work sets forth the critical thoughts of the Abate Sièyes regarding the need to set up a body for the protection of the Constitution. Sièyes ¿the intelectual author of the distinction between constituent power and constituted power, and one of the ...
Javier Tajadura Tejada
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Relação cintura-quadril e fatores de dieta em adultos

open access: yesRevista de Saúde Pública
OBJETIVO: Avaliar as associações entre fatores de dieta e acúmulo de tecido adiposo na região abdominal. MÉTODOS: A partir de um inquérito de base domiciliar realizado no Município do Rio de Janeiro, RJ, em 1995 e 1996, foi investigada a dieta usual em 2.
Paula Aballo Nunes Machado   +1 more
doaj  

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Indigenous constitutional recognition: the concept of consultation [PDF]

open access: yes
INTRODUCTION I was asked to make some remarks about the concept of‘consultation’ in the proposal for Indigenous constitutional recognition put forward by the Cape York Institute (‘CPI’).
Cheryl Saunders
core  

Guarding the Guardians? Towards an Independent, Accountable and Diverse Senior Judiciary [PDF]

open access: yes, 2012
At the heart of what Vernon Bogdanor has described as the ‘The New British Constitution’ has been the rise in the political significance of the judiciary.
Paterson, Alan, Paterson, Chris
core  

On material-uniform elastic bodies with disclinations and their homogenization [PDF]

open access: yesarXiv
In this note, we define material-uniform hyperelastic bodies (in the sense of Noll) containing discrete disclinations and dislocations, and study their properties. We show in a rigorous way that the size of a disclination is limited by the symmetries of the constitutive relation; in particular, if the symmetry group of the body is discrete, it cannot ...
arxiv  

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