Results 101 to 110 of about 5,443,273 (334)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Knowledge and attitude towards body donation among students in Huye campus, University of Rwanda

Rwanda Medical Journal
INTRODUCTION: Body donation is the willingness of a person to donate his body or organ to a person or organization after death. Medical schools in Western countries depend solely on human donations for medical education.
V. Archibong, A. Mohammed, A. Afodun, A. Okesina, S. Olurunnado, A. Ivan, K. Okesina, J. Gashegu   +7 more
doaj   +1 more source

Changes in Body Weight Before and After Kidney Donation

Canadian Journal of Kidney Health and Disease, 2019
Background: Living kidney donors remain at low risk of end-stage kidney disease (ESKD), but the risk for obese and overweight donors is increased. The Kidney Disease Improving Global Outcomes (KDIGO) clinical guideline recommends that overweight and ...
Ann Bugeja, Sophie Harris, Jaclyn Ernst, Kevin D. Burns, Greg Knoll, Edward G. Clark   +5 more
doaj   +1 more source

The lady vanishes: what's missing from the stem cell debate [PDF]

, 2006
Most opponents of somatic cell nuclear transfer and embryonic stem cell technologies base their arguments on the twin assertions that the embryo is either a human being or a potential human being, and that it is wrong to destroy a human being or ...
A. Fagot-Largeault, A. Jacobs, A. M. Honore, A. Ryan, C. A. MacKinnon, C. McLeod, C. Pateman, C. Waldby, CCNE (Comite Consultatif National d’Ethique), CCNE (Comite Consultatif National d’Ethique) and Nationaler Ethikrat. Opinion no. 77, D. B. Resnik, D. Dickenson, D. Dickenson, D. Dickenson, D. Dickenson, D. Dickenson, D. Dickenson, D. Dickenson, Donna L. Dickenson, E. Marshall, G. A. Cohen, G. Meilander, G. W. F. Hegel, HUGO (Human Genome Organisation) Ethics Council, I. Schneider, J. Boyle, J. E. Penner, J. E. Penner, J. L. Schroeder, J. Locke, J. Mahoney, J. McHale, J. Montgomery, J. W. Harris, J. Waldron, K. E. Ferguson, K. Momberger, L. Brace, M. J. Radin, R. Macklin, R. R Faden, Royal College of Obstetricians and Gynaecologists (RCOG) Ethics Committee, S. Dodds, S. E. Lanzendorf, S. Holland, S. Holm, T. Grey, T. Harrison, T. Murray, W. E. Connolly, W. S. Hwang   +50 more
core   +2 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

BLOOD DONATION – A VITAL PRACTICE IN THERAPY AND LIFE-SAVING: HEALTH BENEFITS AND IMPACT ON WELL-BEING

Biota. Human. Technology
Purpose: The aim of this article is to provide a detailed analysis of the health benefits of blood donation, with particular emphasis on its effects on cardiovascular function, iron regulation, lipid metabolism, blood pressure and the prevention of ...
Małgorzata Gradziuk, Halina Tkaczenko, Natalia Kurhaluk   +2 more
doaj   +1 more source

A proposal for body donation forms in Turkey: study of the Committee for Body Donation and Cadaver Monitoring

Anatomy, 2020
Informed consent is an integral part of daily anatomical practice. Providing adequate information regarding body donation process and emphasizing the importance of use of donated bodies in anatomy education will help the individuals who consider body ...
I. Gürses, Servet Çelik, Mehmet Üzel, Ç. Barut, Zeliha Kurtoğlu Olgunus, Okan Bilge   +5 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source