Results 131 to 140 of about 5,443,273 (334)

Higher abdominal fat area associates with lower donor kidney function before and after living kidney donation

Scientific Reports
Central body fat distribution affects kidney function. Abdominal fat measurements using computed tomography (CT) may prove superior in assessing body composition-related kidney risk in living kidney donors.
Lisa B. Westenberg, Marco van Londen, Marcel Zorgdrager, Mara A. McAdams-DeMarco, Dorry L. Segev, Stephan J. L. Bakker, Alain R. Viddeleer, Robert A. Pol   +7 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Reverse Transplant Tourism [PDF]

, 2014
In this article, we propose a novel form of kidney swap, which we label “Reverse Transplant Tourism.” This proposal has the potential to increase the number of successful transplants in the US at a time of great need, while reducing costs.
Krawiec, Kimberly D., Rees, Michael A.
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Addressing spiritual beliefs and legal barriers from the Alaigbo perspective to the establishment of body donation programs for African anatomy education and global medical advancement

Discover Education
The globalization of body bequest programs for medical education continues to face significant challenges in Africa, despite guidelines and recommendations aimed at promoting ethical body donation practices.
Boniface Ezenwata Echefu
doaj   +1 more source

A retrospective study on the carbon footprint of bodies donated to science for sustainable medical education and research

Frontiers in Medicine
IntroductionA comprehensive understanding of human anatomy is essential for medical education, with donated human body dissection remaining the gold standard for this purpose.
Carlo Barausse, Carlo Barausse, Subhi Tayeb, Lorenzo Bonifazi, Simone Lodi, Giulia Adalgisa Mariani, Ester Orsini, Sara Zanni, Alessandra Bonoli, Lucia Manzoli, Stefano Ratti   +10 more
doaj   +1 more source

The Attitude of Medical Students Toward Voluntary Body Donation: A Single Institute Survey and Narrative Review of Global Trends. [PDF]

Cureus, 2023
Ganapathy A, Joy P, Rout S, Gaikwad M.
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Iowa Office of the State Medical Examiner Newsletter, September 1, 2008, no. 4 [PDF]

, 2008
The official newsletter of the Iowa Office of the State Medical ...

core