Results 101 to 110 of about 15,189,752 (297)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

The effect of body mass change on cycling efficiency [PDF]

open access: yes, 2016
Cycling efficiency is a measure of the ability to convert stored energy into power, and is considered a key determinant of cycling performance. Cycling efficiency has recently been manipulated with various techniques, but most prominently with high ...
Saunders, S.
core  

BODY COMPOSITION OF ONGOLE CROSSBRED GROWING BULL UNDER INTENSIVE FEEDING MANAGEMENT [PDF]

open access: yes, 2008
The objective of this study was to evaluate the correlation between age and body composition of ongole crossbred growing bull under intensive feeding management.
Soeparno, Soeparno   +4 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Effect of Body Mass Index on Endometrial Thickness in Postmenopausal Asymptomatic Patients

open access: yesİstanbul Medical Journal, 2015
Objective: To evaluate whether body mass index (BMI) is an important parameter that affects the thickness of the endometrium in asymptomatic postmenopausal women.Methods: Our study was performed retrospectively using computer and file records of 434 ...
Çiğdem Yavuz Yurtsever   +5 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Biodynamics of the seated human body with dual-axis excitation: nonlinearity and cross-axis coupling

open access: yes, 2012
The apparent mass of the seated human body and the transmissibility to the upper-body (i.e., the spine and the pelvis) during vertical vibration excitation have been reported to have resonance frequencies around 5 Hz.
Zheng, Guangtai
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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