Results 31 to 40 of about 73,995 (247)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Pengaruh Body Shaming terhadap Self-Esteem Siswa SMP

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2020
: The existence of a standardized appearance or ideal body, both for men and for women, often triggers body shaming for people who do not comply with these standards. This study aims to investigate the effect of body shaming on students' self-esteem This
Nani Barorah Nasution, Ernita Simanjuntak   +1 more
doaj   +1 more source

SELF-ESTEEM AND BODY ESTEEM AS PREDICTORS OF QUALITY OF LIFE IN EMERGING ADULTS

Facta Universitatis, Series: Philosophy, Sociology, Psychology and History, 2023
The main aim of this study was to determine whether the domains of quality of life can be predicted by the dimensions of body esteem (appearance, weight, attribution) and self-esteem (performance, social) in emerging adults. The Body Esteem Scale, The State Self-Esteem Scale and World Health Organization Quality of Life – Brief were applied. The sample
Mila Guberinić, Miljana Spasić Šnele
openaire   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Body Image in Relation with Stress Level and Self-Esteem Among Adolescents with Thalassemia Major

Althea Medical Journal
Background: Body image influences how adolescents perceive and accept physical changes. Adolescents with thalassemia major require regular blood transfusions, which may lead to iron overload and complications such as bone and skull deformities, growth ...
Felicia Kurniawan, Magdalena Surjaningsih Halim, Surilena Surilena, Elisabeth Eileen Santoso, Sarah Agatha Indra, Valencia Valencia   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Body satisfaction and self-esteem in pregnant women

SERIES VII - SOCIAL SCIENCES AND LAW, 2020
The body image of pregnant women has not been addressed in depth in countries such as Romania. The motivation behind the choice of this theme is the conflict that takes place in the life of a pregnant woman, between the social ideals of the feminine aspect and the changes that take place both physically and mentally.
I. Antonie, M. Vintila, O.I. Tudorel, G. Tetu, C.C. Nanu, M.C. Bularca   +5 more
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Young People Who Sext: The Role of Self-Esteem and Body-Esteem [PDF]

The Central European Journal of Paediatrics, 2021
Objective − The aim of this research was to examine the relationship between sexting, self-esteem and body-esteem. Subjects and Methods − A total of 707 subjects participated in this study of which 138 were male and 551 female students from Bosnia and Herzegovina (N=395), and the Republic of Croatia (N=294). They completed a modified version of the
openaire   +1 more source