Results 171 to 180 of about 8,496,000 (299)

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu, Wanying Chen, Haijiang Qiu, Weihan Zheng, Ying Jiao, Jingheng Du, Zhudan Zhuang, Xing Hua, Jingyi Gu, Yuheng Liu, Zhaojin Li, Jingbin Xie, Hanxiao Sun, Huifei Lan, Xin Sun, Yunxia Xue, Ting Fu, Zhijie Li, Guobing Chen, Shiyu Li, Jun Liu   +20 more
wiley   +1 more source

Association of the TyG index and its body fat distribution composites with CHD and MACE risk in adults with OSAHS: incremental discrimination and exploratory mediation analysis. [PDF]

Front Endocrinol (Lausanne)
Liang Z, Zhu X, Chen Y, Maimaitimin A, Nihemaiti N, Shata G, Maihemutijiang R.   +6 more
europepmc   +1 more source

Association between body fat distribution and B-lymphocyte subsets in peripheral blood. [PDF]

Immun Ageing, 2023
Prechtl P, Schmitz T, Pochert N, Traidl-Hoffmann C, Linseisen J, Meisinger C, Freuer D.   +6 more
europepmc   +1 more source

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

Advanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang, Zuomeng Wu, Ruocheng Guo, Cancan Wang, Yue Qin, Yixiang Dong, Aoyun Li, Ao Liu, Chongyu Jia, Tianyu Han, Peiwen Song, Lei Chen, Cailiang Shen   +12 more
wiley   +1 more source

Body mass index: a measure of fatness or leanness?

, 1995
The relationship between body fat and stature-adjusted weight indices was explored. Assuming the term height’ is a valid indicator of a subject’s lean body mass, heighplweight was shown to be an accurate measure of percentage lean body mass and, as such,
Holder, Roger L., Nevill, Alan M.
core  

The association between body fat distribution and osteosarcopenia in older adults: evidence from the PoCOsteo study. [PDF]

Aging Clin Exp Res
Torabi A, Afrashteh S, Moftian N, Ghalandari H, Farhadi A, Emamat H, Nabipour I, Larijani B.   +7 more
europepmc   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

DEXA-Derived Body Fat Distribution and Its Correlation With Clinical, Anthropometric, Insulin Sensitivity, Metabolic, and Hormonal Parameters Among Kashmiri Polyendocrine Metabolic Ovarian Syndrome (PMOS) Women: A Cross-Sectional Study. [PDF]

Cureus
Yousuf SD, Ahmed W, Qadir A, Rehman NU, Islam KU, Ganie MA.   +5 more
europepmc   +1 more source

Relationships between body fat distribution and metabolic syndrome traits and outcomes: A mendelian randomization study. [PDF]

PLoS One, 2023
Huang B, DePaolo J, Judy RL, Shakt G, Witschey WR, Levin MG, Gershuni VM.   +6 more
europepmc   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source