Results 51 to 60 of about 3,519,002 (294)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

A correlational study of the impact of media influence on the body image of adolescent females [PDF]

open access: yes, 2000
Plan BMagazines, movies, advertisements are all influential forces in our society. Adolescent females are susceptible to this influence. It is important for adolescent females to become aware of the impact of the media to override the messages that our ...
Wickman, Laurel J.
core  

Idealism and the Mind-Body Problem 1 [PDF]

open access: yes, 2019
This chapter examines the prospects for the one who comes to think that there is little reason to believe in anything beyond consciousness and that the physical world is wholly constituted by consciousness, thereby endorsing idealism: the move to idealism.
openaire   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Sociocultural pressures and appearance ideal internalization: Their impact on body dissatisfaction in Brazilian adults

open access: yesPreventive Medicine Reports
Objective: To analyze the relationship between internalization of appearance ideals, sociocultural pressures, and body dissatisfaction among Brazilian adults.
Camila Carla Souza do Prado   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Body perceptions and satisfaction among adults with excess weight in India: a mixed methods approach

open access: yesBMC Psychology
Background The complications of obesity are far beyond just physical health. We assessed body perceptions and satisfaction among adults with excess weight in the Kolkata metropolitan area.
Somdutta Barua, Nandita Saikia
doaj   +1 more source

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