Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Developing a Positive Body Image in Young Women by the Means of Training Technologies
The paper presents the analysis of the positive body image formation among young women, characterizes determinants of female body image and describes the results of an experimental study. The purpose of the study was to test the possibility of developing
Belogai K.N. +4 more
doaj +1 more source
Can body language shape body image?
Proceeding of the 11th International Conference on the Simulation and Synthesis of Living Systems held in Winchester (UK) del 5 al 8 de agosto de 2008.
Steels, Luc, Spranger, Michael
openaire +3 more sources
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Painting baryons onto N-body simulations of galaxy clusters with image-to-image deep learning [PDF]
Urmila Chadayammuri +4 more
openalex +1 more source
Acceptance of psoriasis in the context of body image, body experience, and social support
Background Acceptance of disease is an important determinant of quality of life in psoriasis patients. Social support and positive body image are considered important contributors to coping with the disease, but no studies have yet examined the role of
Olga Sakson-Obada +3 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Multi-Parametric Chest Magnetic Resonance Imaging for Assessment of Local Recurrence of Non-Small Cell Lung Cancer after Stereotactic Body Radiation Therapy [PDF]
Sarit Appel +6 more
openalex +1 more source

