Results 41 to 50 of about 7,180,346 (257)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Body Language in Youtube-Based Product Endorsements by Indonesian Influencers
HumanioraBody language plays a crucial role in non-verbal communication by expressing emotions, attitudes, and intentions. Its dynamic nature allows individuals to convey diverse meanings, particularly in professional and business settings.
Menik Winiharti, Hensen Hensen
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Nonverbal communication in the context of individual violin lessons
Per Musi, 2022 This article resulted from a naturalistic investigation, quali-quanti, being a case study, in its multi-case aspect. As an objective, the importance of certain nonverbal communication in violin lessons was identified.
Francisco Parente Ramos +1 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Note sulla pelle dei delinquenti
DNA Di Nulla Academia, 2022 Prison is hell. Tullio Murri lived it for many years and told the sad life of the prisoners, describing characters, behaviors and bodies. A few decades earlier, Cesare Lombroso also studied the physical appearance of criminals: the tattoo, for example ...
Lucia Rodler
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
An In-Depth Look at Fonni’s Dog Behavior under Different Outdoor Conditions
AnimalsThis study aimed to investigate the common social and communicative behaviors of the Fonni’s Dog under different outdoor conditions. For this study, 70 adult dogs (3–7 years; 32 intact males, 38 intact females) belonging to the Fonni’s breed were used. A
Raffaella Cocco +5 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Nonverbal communication of trauma patients in a state of minimal consciousness
Annals of Agricultural and Environmental Medicine, 2019 Introduction In spite of the rapid development in various communication-support technologies for those waking up from a coma, studies describing the sole process of reconstructing communication in this group of patients are scarce.
Anna Rasmus +4 more
doaj +1 more source