Results 141 to 150 of about 594,890 (296)
Excretion in the mother's body: modifications of the larval excretory system in the viviparous dermapteran, Arixenia esau. [PDF]
Protoplasma, 2018 Jaglarz MK, Tworzydlo W, Bilinski SM.
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Transsexual body modifications as narcissistic self-regard, a UK context
, 2005 The aim of my research is to investigate transsexual bodily aesthetics and the use that transsexuals make of body modification technologies in the construction of a gendered identity.
Zowie Davy (17156536)
core +1 more source
La función de la piel y de las modificaciones corporales en la constitución del Yo
Avances en Psicología Latinoamericana, 2012 In object relation theory and particularly in Esther Bick’s theory, skin has a mayor function in the process of the Self constitution; with Bick’s concept of skin as a container, the role of this body organ as a mediator in the integration of parts of ...
Laura Franco Cian +1 more
doaj
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Excessive lipid contents in immature oocytes from repeat breeder dairy heifers
, 2006 The repeat breeding problem in cattle is widespread among all the heavy dairy breeds in cattle and is being considered as a major problem throughout the world. The aetiology of the repeat breeding is of various origins.
Awasthi, Hitesh
core
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source