Results 71 to 80 of about 594,890 (296)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Early European evidence of artificial cranial modification from the Italian Late Upper Palaeolithic Arene Candide Cave

Scientific Reports
This study reports on early Eurasian evidence of artificial cranial modification (ACM) in a Late Upper Palaeolithic (LUP) individual (AC12) from Arene Candide Cave, Italy (ca. 12,620–12,190 Cal BP).
Tommaso Mori, Vitale Stefano Sparacello, Alessandro Riga, Giorgia Ciappi, Dario Ferrari, Francesca Seghi, Fabio Di Vincenzo, Monica Zavattaro, Filippo Pasquinelli, Roberto Carpi, Marco Peresani, Federica Fontana, Luca Sineo, Jacopo Moggi-Cecchi, Irene Dori   +14 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

“Quotations” in headlines: their analysis in two German regional newspapers as a contribution to the topic of language usage in the media / „Zitate“ in Schlagzeilen: eine medienlinguistische Untersuchung am Beispiel zweier deutscher Regionalzeitungen

Kalbotyra, 2008
Based on a corpus of articles from two regional subscription newspapers representing the most widespread type of daily papers in Germany, this contribution analyses quotations in headlines of press articles and their relation to the corresponding ...
Klaus Geyer
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Body Modification as Body Art

Atlantis
In this article, I discuss my “anti-aging” body modification practices as body art. The art documents my bodybuilding programs, self-administered neurotoxin (Botox) injections, and skin resurfacing treatments. Susan Pickard (2020) argues that femininity and aging are associated with the abject. She maps the abject and non-abject onto Simone de Beauvoir’
openaire   +4 more sources

Kødets fristelser

Akademisk Kvarter, 2010
Steen Christiansens Kødets fristelser. (Temptations of the flesh). In its analysis of the softcore and pin-up-website suicidegirls.com and with a point of departure in tattoos, piercings and other body modifications the article discusses flesh as an ...
Steen Christiansen
doaj   +1 more source

Post-translational Modifications of IκBα: The State of the Art

Frontiers in Cell and Developmental Biology, 2020
The nuclear factor-kappa B (NF-κB) signaling pathway regulates a variety of biological functions in the body, and its abnormal activation contributes to the pathogenesis of many diseases, such as cardiovascular and respiratory diseases and cancers ...
Xiuli Wang, Hanlin Peng, Yaqian Huang, Wei Kong, Wei Kong, Qinghua Cui, Junbao Du, Junbao Du, Hongfang Jin   +8 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Effect of Intake Manifold Porting and Polishing and Throttle Body Venturi Diameter Modification on Motorcycle Performance

Jurnal Teknik Mesin
This study aims to investigate the effect of intake manifold and throttle body modifications on the performance of a Yamaha Mio M3 125cc motorcycle engine. A two-level factorial experimental design with two factors was employed: intake manifold diameter (
GUN GUN ANBIA
doaj   +1 more source