Results 111 to 120 of about 191,418 (345)
Zimbabwean medication use in New Zealand: The role of indigenous and allopathic substances [PDF]
, 2012 Over millennia, indigenous communities have developed distinct health systems and a range of medications. Many of these traditions have been disrupted, delegitimised and changed through processes of colonisation.
Groot, Shiloh Ann Maree +3 more
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
H3K4me3 binding ALFIN-LIKE proteins recruit SWR1 for gene-body deposition of H2A.Z
Genome BiologyBackground The H2A.Z histone variant is highly enriched over gene bodies, playing an essential role in several genome-templated processes, including transcriptional regulation and epigenetic patterning across eukaryotes.
Linhao Xu +7 more
doaj +1 more source
Torque and Flow Pattern of Gas-Liquid Two-Phase Flow Driven by a Rotating Body
, 2021 Naoyuki KINAMI +2 more
openalex +2 more sources
Effect of Patterned Slip on Micro and Nanofluidic Flows
, 2005 We consider the flow of a Newtonian fluid in a nano or microchannel with walls that have patterned variations in slip length. We formulate a set of equations to describe the effects on an incompressible Newtonian flow of small variations in slip, and ...
C. Cottin-Bizonne +7 more
core +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Activation patterns in atrial fibrillation: contributions of body surface potential mapping. [PDF]
, 2008 Maria De La Salud Guillem Sanchez
openalex +1 more source
Thoracolumbar curve behavior after selective thoracic anterior vertebral body tethering in Lenke 1A vs Lenke 1C curve patterns [PDF]
, 2023 Michelle C. Welborn +5 more
openalex +1 more source
, 2016 This research has departed from the standard method of flat surface binding of mesh pieces that requires various transformations and restrictions, and instead has attempted to conceive a novel approach that can develop 3D body surfaces into 2D level. Opposed to existing standard pattern flattening method which took utmost reflection of 3D body surface ...
Jinhee Park, Yun-Ja Nam
openaire +2 more sources
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source