Results 111 to 120 of about 3,364,566 (294)
Start small: A model for tissue-wide planar cell polarity without morphogens.
PLoS Computational BiologyPlanar cell polarity (PCP) is an important patterning mechanism in both vertebrates and invertebrates by which cells coherently polarize along the apical surface of the epithelium.
Abhisha Thayambath, Julio M Belmonte
doaj +1 more source
Body based patterns. : The human body as a tool for designing surface patterns
, 2020 This degree work places itself in the field of textile design, surface patterns and conceptual design. The aim of the work is to use the human body as a tool for designing conceptual surface patterns onto textiles. The methods of designing were done through practical workshops.
openaire +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Fatness and Fat Patterning as Independent Anatomical Characteristics of Body Composition: A Study of Urban South African Children [PDF]
, 2014 Objective: The purpose of this study was to examine the relationship between fat patterning, age and body composition, among urban South African children in Pretoria, Central.
Goon, Daniel Ter
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
H3K4me3 binding ALFIN-LIKE proteins recruit SWR1 for gene-body deposition of H2A.Z
Genome BiologyBackground The H2A.Z histone variant is highly enriched over gene bodies, playing an essential role in several genome-templated processes, including transcriptional regulation and epigenetic patterning across eukaryotes.
Linhao Xu +7 more
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Young Children's Mathematical Patterning [PDF]
, 2005 YOUNG CHILDREN'S MATHEMATICAL PATTERNING\ud Jillian Fox\ud Queensland University of Technology, Brisbane, Australia\ud Mathematical patterning is fundamental to the development of mathematics.
Fox, Jillian L.
core
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source