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Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
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Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
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Distortion of mental body representations
Trends in Cognitive Sciences, 2022Our body is central to our sense of self, and distorted body representations are found in several serious medical conditions. This paper reviews evidence that distortions of body representations are also common in healthy individuals, and occur in domains including tactile spatial perception, proprioception, and the conscious body image. Across domains,
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Somatosensory processing and body representation
Cortex, 2009Recent years have seen increasing numbers of transcranial magnetic stimulation (TMS) studies focusing on somatosensory processing. Most have centered on the primary somatosensory functions of tactile detection, localization and discrimination, and have applied TMS to primary somatosensory areas.
Elena, Azañón, Patrick, Haggard
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Body representations and brain damage
Neurophysiologie Clinique/Clinical Neurophysiology, 2014We review changes in body representation in patients with brain hemisphere damage and discuss their relationship with impaired limb movements in peripersonal space, navigation between objects/obstacles and control of the body's general posture and balance.
Rousseaux, Marc +2 more
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Body-centered representation and perception
1995Intuitive notions of shape, object, and part are informative for perception and modeling. Intuitive sense of shape is a volume concept, not a surface concept; shape relates surfaces typically as ratios of diameters.
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Multisensory Integration in Body Representation
To be aware of and to move one's body, the brain must maintain a coherent representation of the body. While the body and the brain are connected by dense ascending and descending sensory and motor pathways, representation of the body is not hardwired.Wen, Fang, Yuqi, Liu, Liping, Wang
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The Representation of the Beloved’s Body
2021In this chapter, the theme of how the beloved’s body is represented is set within the generic conventions of classical Arabic poetry. Particular attention is drawn to the image of a corpulent woman and the depiction of a woman as a gazelle. The chapter also contains an extended treatment of what might be termed the ethereal aspects of female beauty in ‘
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The effect of viewpoint on body representation in the extrastriate body area
NeuroReport, 2004Functional neuroimaging has revealed several brain regions that are selective for the visual appearance of others, in particular the face. More recent evidence points to a lateral temporal region that responds to the visual appearance of the human body (extrastriate body area or EBA).
A. W. Chan +2 more
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