Results 41 to 50 of about 493,888 (296)
Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers [PDF]
, 2014 We previously used a single nucleotide polymorphism (SNP) in the CHRNA5-A3-B4 gene cluster associated with heaviness of smoking within smokers to confirm the causal effect of smoking in reducing body mass index (BMI) in a Mendelian randomisation analysis.Kumari, Meena, Paternoster, Lavinia, Postmus, Iris, Bjørngaard, Johan Håkon, Frayling Tim, Räikkönen, Katri, Munafò, Marcus R., Caroline Hayward (149856), Power Christine, Ahluwalia, TS, Sorensen, Thorkild I. A., Kirsten Ohm Kyvik (75576), Gabrielsen, Maiken Elvestad, Johan H Bjorngaard, Christiansen, Lene, Meg E. Fluharty (669886), Kyvik, KO, Smith, BH, Sandosh Padmanabhan (238533), Padmanabhan Sandosh, Wannamethee S. Goya, Morris Richard W., Kaprio, Jaakko, Cavadino, Alana, Peter H Whincup, Wannamethee, S. Goya, Whincup, PH, Martin Preisig, Vink, JM, Ford, I, Davey Smith George, Hällfors Jenni, Marioni, Riccardo R., Kyvik, Kirsten Ohm, Marques-Vidal, P, Marques-Vidal Pedro, Davey Smith, George, Cavadino, A, Skaaby, Tea, Vink, J.M., Lawlor, Debbie, Taylor Amy E., Ohm Kyvik, Kirsten; id_orcid, Wannamethee, S Goya, Marika Kaakinen, Taylor, A.E., Lavinia Paternoster (153181), Treur, J., Eriksson, Johan, Ahluwalia, T., Dale, C., Munafò, MR, Iris Postmus, Watt, G, Husemoen, Lise Lotte N., Treur, J.L., J. Wouter Jukema (127361), Jarvelin, Marjo-Riitta, Kisialiou Aliaksei, Nohr, EA, Davey Smith, G., Jukema, JW, Wong, A., Jari Lahti, Hällfors, J., Paternoster, L., Romundstad Pål R., Sattar, N, Smith, GD, Fergusson, D., Aarno Palotie (41342), Palotie, A, Ian Ford, Pål R Romundstad, Martin A Kennedy, Lavinia Paternoster, Dale Caroline, Kaprio Jaakko, Wannamethee, SG, Hyppönen, E., Tim Frayling, Eriksson, J, Linneberg Allan, Naveed Sattar, Ford, Ian, et al., Jenni Hällfors (669893), Dalgård, Christine, Postmus Iris, Fluharty, M.E., Tarunveer S. Ahluwalia (418885), Maiken E Gabrielsen, Linneberg, A., Husemoen, L., Palotie, A., Christine Dalgård, Bjørn Olav Åsvold (669889), Jarvelin Marjo-Riitta, Sorensen, TIA, Kisialiou, A., David M Fergusson, Husemoen, LL, Sørensen, Thorkild I. A., Bjorngaard, J.H., Bjorngaard, Johan H., Andrew Wong (256256), Treur, Jorien L, Ahluwalia, Tarunveer Singh, Alex McConnachie, Fergusson, DM, Ahluwalia, Tarunveer S, Lene Christiansen, Sørensen, Thorkild I.A., George Davey Smith, Sørensen, T.I.A., Hyppönen, Elina, Graham Watt (246706), Borodulin, Katja, Ohm Kyvik Kirsten, Ohm Kyvik, K., Campbell, A., Kuh, D., Kumari Meena, Andrew Wong, Borodulin Katja, Wong, A, Jari Lahti (149903), Husemoen, LLN, Fergusson, D, Frayling, Tim, Richard W Morris, Eriksson Johan, Asvold, B.O., Räikkönen Katri, Ellen A. Nohr (162402), Elina Hyppönen (163747), Männistö, Satu, McConnachie, A, Johan Eriksson, Alana Cavadino (448066), Smith, B.H., Martin Preisig (111534), Elina Hyppönen, Johan Eriksson (131534), Lene Christiansen (158189), Lahti, J., Marioni, R, Kaakinen Marika, Jukema, J.W., Fergusson David M., Whincup, P.H., Preisig, M, Gabrielsen, Maiken E., Pål R. Romundstad (420886), Power, C, Tyrrell, Jessica, Katja Borodulin, Archie Campbell (669891), Taylor, Amy E., McConnachie Alex, Kivimaki Mika, Smith, Blair H., Meg E Fluharty, Tea Skaaby (292885), Ben-Shlomo, Y., Preisig, Martin, Marjo-Riitta Jarvelin (110290), Marioni, R., Borodulin, K., Kumari, M., Jarvelin, MR, Hällfors, J, Sørensen, TI, Kennedy, M.A., Fluharty, ME, Fluharty, M., Alex McConnachie (104022), Vink Jacqueline M., Ben-Shlomo, Y, Nohr, Ellen A, Ian Ford (30666), Dalgård Christine, John Horwood (669895), Nohr Ellen A., Nohr, Ellen A., Smith, Blair H.; id_orcid, Munafo, M.R., Tarunveer S Ahluwalia, Satu Männistö, Taylor, Amy E, Romundstad, P.R., Marika Kaakinen (116620), Kisialiou, A, Marcus R Munafò, Männistö, S, Vink, Jacqueline M, Kennedy Martin A., Kivimaki, M., Tyrrell, J, Horwood, J., Postmus, I, Bjorngaard, Johan H, Hayward, C, Asvold, Bjørn Olav, Sørensen, Thorkild I A, Amy E. Taylor (111604), Horwood, John, Linneberg, A, Lawlor, D, Aliaksei Kisialiou (267828), Jessica Tyrrell (482364), Debbie Lawlor, Kivimaki, M, Jacqueline M Vink, Ohm Kyvik, K, Christine Power, Whincup, Peter H., Marjo-Riitta Jarvelin, Munafò Marcus R., Asvold, Bjorn Olav, Watt, G., Hyppönen Elina, Marioni, Riccardo, Ford Ian, Sørensen Thorkild I. A., Romundstad, PR, Yoav Ben-Shlomo, Watt, Graham, Åsvold Bjørn Olav, Kumari, M, Pedro Marques-Vidal, Jaakko Kaprio (43154), Frayling, T, Fergusson, D.M., Ellen A Nohr, Palotie Aarno, Satu Männistö (201550), Kaakinen, M, Maiken E. Gabrielsen (669890), Sorensen, T.I.A., Pedro Marques-Vidal (58558), Allan Linneberg, Martin A. Kennedy (278135), Katja Borodulin (669897), Sørensen, Thorkild IA, Jessica Tyrrell, Kaakinen, Marika, Bjorngaard, J., Hayward, C., Åsvold, BO, Kivimaki, Mika, Jukema, J. Wouter, Christiansen, L., Jorien L Treur, Jukema, J Wouter, Fluharty, Meg E, Sattar Naveed, Marques-Vidal, Pedro, Power, Christine, Horwood John, Bjorngaard, JH, Archie Campbell, Kuh, Diana, Campbell, A, Naveed Sattar (8785), Dorret I Boomsma, Gonneke Willemsen (75573), Räikkönen, K, Blair H. Smith (625812), Whincup, Peter H, J Wouter Jukema, Sattar, Naveed, Diana Kuh, Palotie, Aarno, Kaprio, J., Christine Power (448073), Dorret I. Boomsma (109746), Dale, C, Kirsten Ohm Kyvik, Thorkild I. A. Sørensen (37671), Ahluwalia, Tarun Veer Singh, Mika Kivimaki (2222011), S Goya Wannamethee, Kuh Diana, Cavadino Alana, George Davey Smith (82619), Smith, G.D., Husemoen, Lise Lotte N, Hyppönen, E, Nohr, Ellen A; id_orcid, Frayling, T., Dale, Caroline, Kennedy, MA, Boomsma Dorret I., Eriksson, J., Morris, R., Richard W. Morris (351802), Power, C., Lahti, Jari, Åsvold, B., Tyrrell Jessica, Lawlor, D., Willemsen, Gonneke, Jarvelin, M-R, Campbell, Archie, Sorensen, Thorkild, Borodulin, K, Dalgård, C, Jenni Hällfors, Padmanabhan, Sandosh, Katri Räikkönen (149957), Männistö Satu, Lise Lotte N. Husemoen (244333), Fluharty Meg E., Morris, RW, Horwood, L.J., Marioni Riccardo, Kennedy, Martin A., Blair H Smith, Gonneke Willemsen, Romundstad, Pål R., Ahluwalia Tarunveer S., Dalgård, Christine; id_orcid, Ohm Kyvik, Kirsten, Skaaby Tea, Marques-Vidal, P., Davey Smith, G, Kaprio, J, Jukema J. Wouter, Treur, Jorien L., Kuh, D, Watt Graham, Willemsen, G, Caroline Hayward, Boomsma, D.I.; id_orcid, Allan Linneberg (139773), Tea Skaaby, Männistö, S., Morris, R.W., Taylor, AE, Marcus R. Munafò (171830), Boomsma, Dorret I, Fergusson, David M, Riccardo Marioni (669892), Christiansen, L, Cavadino, A., Caroline Dale, Campbell Archie, Lahti, J, Ahluwalia, Tarunveer S., Willemsen, G.; id_orcid, Morris, Richard W., Bjørn Olav Åsvold, Caroline Dale (448065), David M. Fergusson (278134), Munafò, Marcus R, Meena Kumari (95278), Romundstad, Pål R, Graham Watt, Hayward Caroline, Taylor, A., Johan H. Bjorngaard (669888), Postmus, I., Smith, George Davey, Bjorngaard Johan H., Treur Jorien L., Paternoster Lavinia, Nohr, E.A., Boomsma, Dorret I., Husemoen, L.L., Ben-Shlomo, Yoav, Hayward, Caroline, Husemoen, L.L.N., Kaakinen, M., Smith Blair H., Sattar, N., Smith, Blair H, Lawlor, Debbie A, Ford, I., Linneberg, Allan, Romundstad, Pål Richard, Willemsen Gonneke, Alana Cavadino, S. Goya Wannamethee (669283), Lahti Jari, Wong Andrew, Vink, Jacqueline M., Peter H. Whincup (168892), Debbie Lawlor (669896), Kennedy, Martin A, Aarno Palotie, Boomsma, DI, Yoav Ben-Shlomo (95286), Lawlor Debbie, Katri Räikkönen, Padmanabhan, S, Gabrielsen Maiken E., Preisig Martin, Riccardo Marioni, Lise Lotte N Husemoen, Christine Dalgård (323021), Morris, Richard W, Mika Kivimaki, Järvelin, M.R., Treur, JL, Fluharty, Meg E., Amy E Taylor, Wannamethee, S.G., Meena Kumari, Räikkönen, K., Willemsen, G., Preisig, M., Husemoen Lise Lotte N., McConnachie, A., Jacqueline M. Vink (109713), Aliaksei Kisialiou, Padmanabhan, S., Hällfors, Jenni, Ahluwalia, T.S., Tim Frayling (157530), Horwood, J, Jaakko Kaprio, Gabrielsen, Maiken E, McConnachie, Alex, Boomsma, D.I., Fluharty, Meg, Fergusson, David M., Thorkild I A Sørensen, Frayling, T.M., Skaaby, T, Kisialiou, Aliaksei, Gabrielsen, M., Sørensen, T.I., Iris Postmus (312601), Skaaby, T., Christiansen Lene, Kyvik, K.O., Whincup Peter H., Jorien L. Treur (669894), Dalgard, C., Tyrrell, J., Sandosh Padmanabhan, Hayward, Caroline; id_orcid, Gabrielsen, ME, John Horwood, Wong, Andrew, Paternoster, L, Ben-Shlomo Yoav, Gabrielsen, M.E., Diana Kuh (188923) +449 morecore +1 more sourceThe association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts [PDF]
, 2007 A SNP upstream of the INSIG2 gene, rs7566605, was recently found to be associated with obesity as measured by body mass index (BMI) by Herbert and colleagues.Emilsson, Valur, Fox, Caroline S., Abecasis, Gonçalo, Soto-Quiros, Manuel E., Butler, Johannah L, Pfeufer, Arne, Augustine Kong, Weiss, Scott, Benjamin A Raby, Heid, Iris M., Jessica Lasky-Su, Kristina Bengtsson, Bengtsson, Kristina, Xiaofeng Zhu, Stefansson, Kari, Gulcher, Jeffrey, Joel N Hirschhorn, Fox, Caroline, Johannes Hebebrand, Tiinamaija Tuomi, Juan C Celedón, H Erich Wichmann, Butler, Johannah L., Hirschhorn, Joel, Winfried Rief, Johannah L Butler, Lund University., G Bragi Walters, Cooper, Richard S, Silverman, Edwin K., Zhu, Xiaofeng, Cooper, Richard S., Scott T Weiss, Rief, Winfried, Steinunn Gunnarsdottir, Celedón, Juan C, Iris M Heid, Christoph Lange, Nan Laird, Klanderman, Barbara, Silverman, Edwin, Arne Pfeufer, Anke Hinney, Kong, Augustine, Scherag, Andre, Broenner, Guenter, Caroline S Fox, Vollmert, Caren, Hinney, Anke, Kari Stefansson, Brönner, Günter, Soto-Quiros, Manuel E, Celedon, Juan C., Günter Brönner, Weiss, Scott T., O'Donnell, Christopher, Unnur Thorsteinsdottir, Wichmann, Heinz-Erich, Thorleifsson, Gudmar, Thuy Trang Nguyen, Nguyen, Thuy Trang, André Scherag, Groop, Leif,, Lydiana Avila, Helen N Lyon, Lange, Christoph, Raby, Benjamin, Laird, Nan, Heid, Iris M, Hebebrand, Johannes, Hirschhorn, Joel N., Gudmar Thorleifsson, Edwin K Silverman, O'Donnell, Christopher J., Walters, G. Bragi, Wichmann, H. Erich, Barbara Klanderman, Lasky-Su, Jessica, Valur Emilsson, Thorsteinsdottir, Unnur, Meitinger, Thomas, Gunnarsdottir, Steinunn, Caren Vollmert, Lyon, Helen N., Jeffrey Gulcher, Isomaa, Bo, Raby, Benjamin A., Thomas Meitinger, Leif Groop, Christopher J O'Donnell, Ding, Xiao, Groop, Leif, Manuel E Soto-Quiros, Bo Isomaa, Xiao Ding, Avila, Lydiana, Richard S Cooper, Tuomi, Tiinamaija +97 morecore +1 more sourceTransferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti +9 morewiley +1 more sourceEstablishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns +10 morewiley +1 more source
