Results 91 to 100 of about 5,186,159 (320)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Habeas Corpus: The Sense of Ownership of One ' s Own Body [PDF]
, 2007 What grounds my experience of my body as my own? The body that one experiences is always one's own, but it does not follow that one always experiences it as one's own.
De Vignemont, Frédérique
core +1 more source
A Rule-Based Approach to Analyzing Database Schema Objects with Datalog
, 2017 Database schema elements such as tables, views, triggers and functions are typically defined with many interrelationships. In order to support database users in understanding a given schema, a rule-based approach for analyzing the respective dependencies
A Behrend +13 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
More on Unfold/Fold Transformations of Normal Programs: Preservation of Fitting's Semantics [PDF]
, 1994 The unfold/fold transformation system defined by Tamaki and Sato was meant for definite programs. It transforms a program into an equivalent one in the sense of both the least Herbrand model semantics and the Computed Answer Substitution semantics.
Bossi, Annalisa, Etalle, Sandro
core +4 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Embodiment, Transparency and the Disclosiveness of Failure [PDF]
, 2012 In this paper, I want to argue that embodiment is characterised by a plasticity which entails that it can include both the biological limb and the ‘artificial’ tool, as evidenced by recent research in cognitive science.
May, Shaun
core +1 more source
Preparing Laboratory and Real-World EEG Data for Large-Scale Analysis: A Containerized Approach. [PDF]
, 2016 Large-scale analysis of EEG and other physiological measures promises new insights into brain processes and more accurate and robust brain-computer interface models.
Bigdely-Shamlo, Nima +2 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
More than skin deep: body representation beyond primary somatosensory cortex [PDF]
, 2010 The neural circuits underlying initial sensory processing of somatic information are relatively well understood. In contrast, the processes that go beyond primary somatosensation to create more abstract representations related to the body are less clear.
Azanon, E. +2 more
core +1 more source