Results 91 to 100 of about 5,682,807 (313)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Physical pain, attention and body schema: some phenomenological considerations about the nature of pain [PDF]

, 2016
Con el objetivo de esclarecer algunos de los aspectos más significativos de los análisis fenomenológicos del dolor físico, en este trabajo pretendo mostrar que la fenomenología del dolor es un caso particular de análisis dentro del marco general de la ...
Díaz Romero, Paula
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Habit and the Extended Mind: Fleshing Out the Extended Mind Theory with Merleau-Pontian Phenomenology

Phenomenology and Mind, 2016
This short essay attempts to flesh out the extended mind thesis by showing the nontrivial role of the body in skilled epistemic action. This is attempted by bringing Merleau-Ponty’s notion of the body schema together with Clark and Chalmers account of ...
Richard Charles Strong
doaj   +1 more source

Ghost hand: My hand is not mine [PDF]

, 2009
Synchronous visuo-tactile stimulation of the type in the rubber hand illusion (RHI)^1-3^ and in out of body experience (OBE)^4,5^ can induce the brain to incorporate external objects or images into a part or whole of body image. Whether in the context of
Shinpei Tatsumi, Shusaku Nomura, Yukio Gunji, Yuta Nishiyama   +3 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Correction due to finite speed of light in absolute gravimeters

, 2011
Correction due to finite speed of light is among the most inconsistent ones in absolute gravimetry. Formulas reported by different authors yield corrections scattered up to 8 $\mu$Gal with no obvious reasons.
Abramowitz M, Arnautov G P, Arnautov G P, Arnautov G P, Cook A H, Feng Y-y, Hanada H, Kacker R, Kuroda K, Murata I A, Nagornyi V D, Nagornyi V D, Niebauer T M, Niebauer T M, Pauli W, Robertsson L, Robertsson L, Rothleitner C, Rothleitner C, Schmerge D, Svitlov S, Thulin A, V D Nagornyi, Y M Zanimonskiy, Y Y Zanimonskiy, Zhang Z, Zumberge M, Zumberge M A   +27 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A Review of Shaun Gallagher: How the Body Shapes the Mind [PDF]

, 2006
With 'How the body shapes the mind', Shaun Gallagher provides a general panoptic of the importance of the body in cognition, based on significant experimental results.
De Vignemont, Frédérique
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source