Results 51 to 60 of about 226,806 (251)
Brain oscillatory activity in adolescent idiopathic scoliosis
Pathophysiology of Adolescent Idiopathic Scoliosis (AIS) is not yet completely understood. This exploratory study aims to investigate two aspects neglected in clinical practice: a defective postural central nervous system control in AIS, and alterations ...
Emanuela Formaggio +7 more
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Body schema acquisition through active learning [PDF]
We present an active learning algorithm for the problem of body schema learning, i.e. estimating a kinematic model of a serial robot. The learning process is done online using Recursive Least Squares (RLS) estimation, which outperforms gradient methods usually applied in the literature.
Ruben Martinez-Cantin +2 more
openaire +4 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A methodological study of virtual self-touch: effects on perception and motor control strategies
IntroductionAdvances in virtual reality technology have facilitated research that leverages the plasticity of body schema. This study investigates whether the use of an avatar habituation method, in which participants voluntarily touch an avatar as a ...
Kotaro Okada +8 more
doaj +1 more source
Validation of XML schema and extraction of human body description format parameters
In this paper, the development of Extensible Markup Language (XML) schema of newly proposed Human body description format (HBDF) is proposed and further, the software and hardware solution for processing and acquiring the anthropometric parameters of the
Kainz Ondrej +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
As indicated by the guidelines of the National Institutes of Health (NIH) and the Italian Society of Obesity Surgery and Metabolic Diseases (SICOB), bariatric surgery is the treatment of choice for severe obesity due to its effectiveness in achieving ...
Beatrice Fava +5 more
doaj +1 more source

