Results 81 to 90 of about 6,030,188 (292)

Common carotid intima media thickness and ankle-brachial pressure index correlate with local but not global atheroma burden:a cross sectional study using whole body magnetic resonance angiography [PDF]

, 2014
Common carotid intima media thickness (CIMT) and ankle brachial pressure index (ABPI) are used as surrogate marker of atherosclerosis, and have been shown to correlate with arterial stiffness, however their correlation with global atherosclerotic burden ...
Belch, Jill J. F.; id_orcid, Belch, Jill J F, Faisel Khan, Stephen J Gandy, Gardner, Michael, Weir-McCall, Jonathan R., Rauchhaus, Petra, Adamson, Carly L., Gandy, Stephen J., Gandy Stephen J., Morris, Andrew D., Rauchhaus Petra, Houston, J. Graeme, Allan D Struthers, Lambert, Matthew A., Matthew A Lambert, J Graeme Houston, Ramkumar Prasad Guntur, Struthers Allan D., Lambert Matthew A., Gardner Michael, Adamson Carly L., Jill J F Belch, Michael Gardner, Khan, Faisel; id_orcid, Petra Rauchhaus, Weir-McCall Jonathan R., Jonathan R Weir-McCall, Khan Faisel, Ramkumar, Prasad Guntur, Khan, Faisel, Belch Jill J. F., Morris Andrew D., Carly L Adamson, Struthers, Allan D., Houston J. Graeme, Andrew D Morris, Prasad Guntur Ramkumar   +37 more
core   +2 more sources

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Body Condition Score and its Relation to Body Weight and Measurements of Local Goats of Andhra Pradesh under Field Conditions

International Journal of Bio-Resource and Stress Management, 2022
The technique of Body Condition Score (BCS) is a means of subjectively assessing the degree of fatness or condition of the live animal. It is a simple, non-invasive, time saving and effective management tool to rank goats according to their body ...
Ch. Venkata Reshma, A. Anitha, S. Jagadeeswara Rao, M. Muralidhar   +3 more
doaj  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

How does mass loss compare with total body score when assessing decomposition of human and pig cadavers? [PDF]

Forensic Sci Med Pathol, 2022
Dawson BM, Wallman JF, Barton PS, Barton PS.   +3 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

The Effect of Different Coverings on Total Body Score Development of Buried Carcasses. [PDF]

Malays J Med Sci, 2021
Teo CH, Hing HL, Hamzah NH, Hamzah SPAA.
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source