Results 81 to 90 of about 1,394,969 (305)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Body Condition Score and its Relation to Body Weight and Measurements of Local Goats of Andhra Pradesh under Field Conditions

International Journal of Bio-Resource and Stress Management, 2022
The technique of Body Condition Score (BCS) is a means of subjectively assessing the degree of fatness or condition of the live animal. It is a simple, non-invasive, time saving and effective management tool to rank goats according to their body ...
Ch. Venkata Reshma, A. Anitha, S. Jagadeeswara Rao, M. Muralidhar   +3 more
doaj  

EFICIÊNCIA REPRODUTIVA E DINÂMICA FOLICULAR DE ÉGUAS CAMPOLINA DE ACORDO COM A CONDIÇÃO CORPORAL

Ciência Animal Brasileira, 2013
The aim of this study was to evaluate the effect of body condition (BC) on the reproductive efficiency and follicular dynamics of mares during the breeding season.
Érika Saltiva Cruz Bender, Eliane Vianna Costa e Silva, Helton Mattana Saturnino   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Genetic relationships between calving interval and body condition score conditional on milk yield

, 2002
Body condition score (BCS) is a useful tool in assessing the energy status of dairy cattle. Previous research has shown that it is heritable and genetically correlated to reproductive performance.
Coffey, M.P., Pryce, J.E., Brotherstone, S.H., Woolliams, John   +3 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

How does mass loss compare with total body score when assessing decomposition of human and pig cadavers? [PDF]

Forensic Sci Med Pathol, 2022
Dawson BM, Wallman JF, Barton PS, Barton PS.   +3 more
europepmc   +1 more source

Effect of Body Condition Score at Calving on Adaptive Immune Function During Early Lactation in New Zealand Dairy Cows: Effect of calving body condition on adaptive immune function

, 2014
The extent of postpartum negative energy balance in dairy cows is positively associated with body condition score (BCS) at calving. Results of epidemiological studies have indicated that calving BCS is positively correlated with several indicators of ...
McGowan, Jacqueline Ellen
core