Results 41 to 50 of about 13,473,291 (285)

A predictive model to estimate fever after receipt of the second dose of Pfizer‐BioNTech coronavirus disease 2019 vaccine: An observational cohort study

open access: yesHealth Science Reports, 2022
Background and Aims Fever after coronavirus disease 2019 (COVID‐19) vaccination is generally a mild and benign event, but can cause excessive anxiety in younger adults.
Satoru Chiba, Kaoru Shinohara
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Epileptic burn injuries in Kashmir valley: Is “Kangri” a boon or bane?

open access: yesIndian Journal of Burns, 2019
Background: During seizure attacks, patients may suffer severe trauma such as deep burns, limb fractures, and head-and-neck injuries. Most burns in epileptic patients occur during major seizures. Such burns are always full-thickness.
Peerzada Umar Farooq Baba   +2 more
doaj   +1 more source

Body surface area is a predictor of maturity status in school children and adolescents

open access: yesBMC Pediatrics, 2023
Background Generally, Body surface area (BSA) changes significantly during growth and maturation. These increases portend a possible relationship between body size as determined by BSA with maturational status in children and adolescents.
Fernando Alvear-Vasquez   +7 more
doaj   +1 more source

Use of Body Surface Area for Dosing of Vancomycin [PDF]

open access: yesThe Journal of Pediatric Pharmacology and Therapeutics, 2019
OBJECTIVES Vancomycin weight-based dosing regimens often fail to achieve therapeutic trough serum concentration in children ≤12 years of age and rigorous studies evaluating efficacy and safety of body surface area (BSA)–based dosing regimens have not been performed.
Elizabeth L, Sawrey   +5 more
openaire   +2 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Inequalities for the Surface Area of Projections of Convex Bodies [PDF]

open access: yesCanadian Journal of Mathematics, 2018
AbstractWe provide general inequalities that compare the surface area S(K) of a convex body K in ℝn to the minimal, average, or maximal surface area of its hyperplane or lower dimensional projections. We discuss the same questions for all the quermassintegrals of K.
Giannopoulos, Apostolos   +2 more
openaire   +3 more sources

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