Results 101 to 110 of about 13,218,268 (383)
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
Germline variants in CDKN2A wild‐type melanoma prone families
Molecular Oncology, EarlyView.Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen +5 more
wiley +1 more source
Three-body radiation dynamics in systems with anisotropic nanoparticles
, 2015 The time evolution of temperatures of anisotropic nanoparticles in two and three-body systems are simulated for various relative orientations. Nanoparticles are immersed in a thermal bath at constant temperature. It is shown that in two-body systems, the
Nikbakht, Moladad
core +1 more source
Loss of largest and oldest individuals of the Montpellier snake correlates with recent warming in the southeastern Iberian Peninsula [PDF]
, 2016 The effects of climate change on organisms are now being extensively studied in many different taxa. However, the variation in body size, usually shrinkage in response to increasing temperature, has received little attention regarding to reptiles. During
Alaminos, Esmeralda +3 more
core +1 more source
Body Temperature Regulation in Hot Environments
PLoS ONE, 2016 Organisms in hot environments will not be able to passively dissipate metabolically generated heat. Instead, they have to revert to evaporative cooling, a process that is energetically expensive and promotes excessive water loss. To alleviate these costs,
Jan‐Åke Nilsson +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
AUTOTEM - Automated geometry meshing and heat conduction calculation [PDF]
, 1971 Temperature distribution for an arbitrary irregular body is calculated by AUTOTEM, which generates required input data automatically by computer. Temperature distribution is calculated for a two-dimensional plane section in /x,y/ coordinates or for an ...
Lee, A. Y., Wells, K. J.
core +1 more source
Finite Temperature Many-Body Theory with the Lipkin Model
, 1993 We have compared exact numerical results for the Lipkin model at finite temperature with Hartree-Fock theory and with the results of including in addition the ring diagrams.
Alhassid +21 more
core +1 more source
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
Natural history of Xenosaurus phalaroanthereon (Squamata, Xenosauridae), a Knob-scaled Lizard from Oaxaca, Mexico [PDF]
Phyllomedusa: Journal of Herpetology, 2005 We made observations on the natural history of a population of the lizard Xenosaurus phalaroanthereon from Oaxaca, Mexico. Females were larger than males (SVL). Most lizards were found completely inside rock crevices.
Julio A. Lemos-Espinal +1 more
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