Results 111 to 120 of about 3,065,013 (355)

Body temperature and its regulation

open access: yesAnaesthesia & Intensive Care Medicine, 2014
Abstract Humans are homeotherms, i.e. they fix their temperature regardless of their environment. This is vital for normal cellular function and for metabolism to be independent of external temperature. The body has a warm ‘core’ and a cooler peripheral ‘shell’ whose role is to regulate heat transfer in and out of the core.
Andrew D. Farmery   +3 more
openaire   +3 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

A simple Solvable Model of Body Motion in a One-dimensional Resistive Medium [PDF]

open access: yesarXiv, 2001
We introduce and solve in closed form a simple model of a macroscopic body propagating in a one-dimensional resistive medium at temperature T. The assumption of completely inelastic collisions between the body and the particles composing the medium leads to a resistive force that is opposite and proportional to the square of the body's ...
arxiv  

Antipsychotic-Related Hypothermia: Five New Cases

open access: yesFrontiers in Psychiatry, 2019
Background: Hypothermia is a potentially fatal adverse effect of antipsychotic drug (APD) use. With only 69 cases described in the literature, the condition is considered rare.Methods: We describe five new cases, in which we estimated the role of ...
Cherryl Zonnenberg   +5 more
doaj   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

open access: yesFEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren   +8 more
wiley   +1 more source

Miniature ingestible telemeter devices to measure deep-body temperature [PDF]

open access: yes, 1976
A telemetry device comprised of a pill-size ingestible transmitter developed to obtain deep body temperature measurements of a human is described. The device has particular utility in the medical field where deep body temperatures provide an indication ...
Fryer, T. B., Pope, J. M.
core   +1 more source

Temperature dependence of single-particle properties in nuclear matter

open access: yes, 2008
The single-nucleon potential in hot nuclear matter is investigated in the framework of the Brueckner theory by adopting the realistic Argonne V18 or Nijmegen 93 two-body nucleon-nucleon interaction supplemented by a microscopic three-body force.
C. Mahaux   +12 more
core   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

Metallic hot wire anemometer [PDF]

open access: yes, 1977
A hot wire anemometer is described which has a body formed of heat resistant metal such as an alloy high in nickel content which supports a probe wire disposed in a V groove in the body.
Lemos, F. R.
core   +1 more source

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