Results 71 to 80 of about 3,013,908 (302)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Forced-Air Warming Provides Better Control of Body Temperature in Porcine Surgical Patients
Veterinary Sciences, 2016 Background: Maintaining normothermia during porcine surgery is critical in ensuring subject welfare and recovery, reducing the risk of immune system compromise and surgical-site infection that can result from hypothermia.
Brian T. Dent +2 more
doaj +1 more source
Concept of a Wearable Temperature Sensor for Intelligent Textile
Advances in Electrical and Electronic Engineering, 2020 This paper proposes the intelligent textile for human body temperature measurement. The main concept of the textile is based on two commercially available LM35DM temperature sensors, knitted electrically conductivity yarns and five areas for press-stud ...
Robert Hudec +3 more
doaj +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Preanesthetic effect of orphenadrine on the ketamine/xylazine mixture in a chick model [PDF]
Iraqi Journal of Veterinary SciencesPreanesthetic drugs play an essential role in general anesthesia for smooth induction and recovery and have multiple pharmacodynamic properties; however, they are considered blockers of histamine receptor type 1. The fundamental goal was to determine the
Ahmed S. Naser, Yasser M. Albadrany
doaj +1 more source
Equation of state and contact of a strongly interacting Bose gas in the normal state
, 2015 We theoretically investigate the equation of state and Tan's contact of a non-degenerate three dimensional Bose gas near a broad Feshbach resonance, within the framework of large-$N$ expansion.
He, Lianyi +3 more
core +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Rectal temperature and conception of inseminated crossbred dairy cows
Boletim de Indústria Animal, 2015 In tropical and subtropical regions animals suffer pronounced heat stress effect on reproductive function, being one of the most noticeable effects the reduction of conception rate.
Henrique Barbosa Hooper +4 more
doaj
Stroboscopic Generation of Topological Protection
, 2010 Trapped neutral atoms offer a powerful route to robust simulation of complex quantum systems. We present here a stroboscopic scheme for realization of a Hamiltonian with $n$-body interactions on a set of neutral atoms trapped in an addressable optical ...
Herdman, C. M. +4 more
core +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source