Results 71 to 80 of about 3,065,013 (355)

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Thermal history modeling of the H chondrite parent body [PDF]

open access: yes, 2012
The cooling histories of individual meteorites can be empirically reconstructed by using ages from different radioisotopic chronometers with distinct closure temperatures. For a group of meteorites derived from a single parent body such data permit the reconstruction of the cooling history and properties of that body.
arxiv   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Atomistic Processes of high-temperature plastic deformation of nanoscale body-centered cubic tungsten [PDF]

open access: yesarXiv, 2023
Much scientific and practical interest is currently focused on the atomic-scale mechanical behaviors of metallic nanocrystals with different crystal structures at room temperature, while the high-temperature plastic deformation in tungsten nanocrystals remains not well understood, due to the technical difficulty in elevating the experimental ...
arxiv  

Black-Body Radiation Correction to the Polarizability of Helium [PDF]

open access: yes, 2011
The correction to the polarizability of helium due to black-body radiation is calculated near room temperature. A precise theoretical determination of the black-body radiation correction to the polarizability of helium is essential for dielectric gas ...
D. A. Varshalovich   +4 more
core   +3 more sources

Body temperature regulation in diabetes [PDF]

open access: yesTemperature, 2016
The effects of type 1 and type 2 diabetes on the body's physiological response to thermal stress is a relatively new topic in research. Diabetes tends to place individuals at greater risk for heat-related illness during heat waves and physical activity due to an impaired capacity to dissipate heat.
Ronald J. Sigal   +2 more
openaire   +2 more sources

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

open access: yesMolecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan   +6 more
wiley   +1 more source

Body temperature and thermal imaging

open access: yesMethods in cattle physiology and behaviour – Recommendations from the SmartCow consortium., 2020
Body temperature data is often used in cattle to assess different reproductive events such as oestrus and pregnancy or to identify prevalence of various infectious diseases. Therefore, recording body temperature is important when considering both the health and reproductive status of livestock. Body temperature is often measured during experiments with
Dineen, Michael   +3 more
openaire   +3 more sources

A Low-Cost Wearable Device to Estimate Body Temperature Based on Wrist Temperature

open access: yesSensors
The remote monitoring of vital signs and healthcare provision has become an urgent necessity due to the impact of the COVID-19 pandemic on the world.
Marcela E. Mata-Romero   +9 more
doaj   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

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