A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn +6 more
wiley +1 more source
Effects of ceiling fan use on cardiovascular autonomic function during simulated indoor overheating in bed-resting older adults. [PDF]
O'Connor FK +4 more
europepmc +1 more source
This study presents an implantable, wireless, battery‐free oximeter that can continuously monitor physiologically consistent regional tissue oxygenation under dynamic changes of blood volume. This is achieved through multiwavelength photoplethysmography and validated both via Monte Carlo simulations and in vivo rat studies. Different stress events were
Anat Usatinsky +12 more
wiley +1 more source
Elevation of body temperature during exercise enhances protection against dexamethasone‑induced skeletal muscle atrophy. [PDF]
Ozerklig B +6 more
europepmc +1 more source
Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans +7 more
wiley +1 more source
Temperature regulation mechanisms of diapause in <i>Coridius chinensis</i> revealed by multi-omics integration: coordinated responses of Brain-Gut-Fat Body. [PDF]
Pang Y +13 more
europepmc +1 more source
Silicone breast implants are presented as a model system for understanding polymer permeation in vivo. Rather than representing material failure, “gel bleed” emerges from solution–diffusion transport‐mediated. By integrating polymer architecture, physicochemical transport, and biointerfacial processes, this review provides a unified framework that ...
D. Bouyer +12 more
wiley +1 more source
The transcriptional cortical response to daily torpor in <i>Phodopus sungorus</i>. [PDF]
Bal LC +6 more
europepmc +1 more source
Upon contact with plasma, lipid nanoparticles (LNPs) rapidly acquire a protein corona (PC) that redefines their biological identity. In calcium‐containing environments, these coronated particles trigger the formation of a gel‐like plasma network, profoundly altering their transport properties and reducing their effective availability.
Serena Renzi +14 more
wiley +1 more source
Effects of transcutaneous electrical acupoint stimulation on body temperature, hemodynamic responses, and recovery in patients undergoing open spinal surgery. [PDF]
Liu Y +5 more
europepmc +1 more source

