Results 101 to 110 of about 12,589,503 (295)

Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs. [PDF]

open access: yes, 2013
Obesity is an established risk factor for type 2 diabetes (T2D) and they are metabolically related through the mechanism of insulin resistance. In order to explore how common genetic variants associated with T2D correlate with body mass index (BMI), we ...
Kolli Srinath Reddy (102301)   +87 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Różnice fluktuacji, dynamiki i dymorfizmu płciowego cech somatycznych, typu budowy i otłuszczenia dzieci i młodzieży w wieku od 4 do 18 lat

open access: yesJournal of Education, Health and Sport, 2015
Mrozkowiak Mirosław, Jazdończyk Paulina. Różnice fluktuacji, dynamiki i dymorfizmu płciowego cech somatycznych, typu budowy i otłuszczenia dzieci i młodzieży w wieku od 4 do 18 lat = Fluctuation, dynamics, sexual dimorphism, somatic features, body types
Mirosław Mrozkowiak   +1 more
doaj   +2 more sources

Body typing of children and adolescents using 3D-body scanning

open access: yesPLOS ONE, 2017
Three-dimensional (3D-) body scanning of children and adolescents allows the detailed study of physiological development in terms of anthropometrical alterations which potentially provide early onset markers for obesity. Here, we present a systematic analysis of body scanning data of 2,700 urban children and adolescents in the age range between 5 and ...
Henry Loeffler-Wirth   +8 more
openaire   +4 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Extra-adrenal regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1:physiological regulator and pharmacological target for energy partitioning [PDF]

open access: yes, 2007
The major glucocorticoid in man, cortisol, plays important roles in regulating fuel metabolism, energy partitioning and body fat distribution.
Walker, Brian R
core   +1 more source

Body mass index, type 2 diabetes, and left ventricular function

open access: yesCardiovascular Diabetology, 2018
A recent study found that among individuals with a preserved left ventricular ejection fraction ≥ 55%, global longitudinal strain was significantly lower in overweight patients (i.e., body mass index ≥ 25 kg/m2) with, but not in those without, type 2 ...
Katrine Dina Musaeus, Manan Pareek
doaj   +1 more source

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