Results 51 to 60 of about 2,845,064 (261)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

INTERBREED AND INTRABREED VARIABILITY IN RABBITS AND ITS ROLE IN BREEDING

open access: yesВавиловский журнал генетики и селекции, 2014
Interbreed and intrabreed variability in basic measurements and body indices was studied in rabbits of the eight most widespread breeds. Three blockiness types were recognized: narrow-bodied, intermediate, and wide-bodied.
N. A. Balakirev, R. M. Nigmatullin
doaj  

An observational study of female body shape characteristics in multiracial Malaysia

open access: yesAUTEX Research Journal
The current study aims to explore the representative and typical female body shapes through in-depth observation and analysis of the diversity in Malaysian female body shape characteristics across different ethnic and age groups, which assists in ...
Yiyan Wang, Zakaria Norsaadah
doaj   +1 more source

PROSES PRODUKSI BODY UPPER GENERATING DRUM TYPE CAP.120 T/H

open access: yesOtopro, 2019
Jurnal ini menjelaskan proses produksi body upper generating drum type CAP.120 T/H. Komponen upper generating drum adalah salah satu komponen pada boiler pipa air yang berfungsi sebagai reservoir campuran air dan uap air, dan juga berfungsi untuk ...
Anggra Fiveriati   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

University proceedings. Volga region. Medical sciences

open access: yesИзвестия высших учебных заведений. Поволжский регион: Медицинские науки
Background. To study the distribution of body types among Gujarati girls. Materials and methods. The objects of the study were 105 Gujrati girls aged 18-20 years.
O.V. Kalmin   +3 more
doaj   +1 more source

Solvable Many-Body Models of Goldfish Type with One-, Two- and Three-Body Forces

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2013
The class of solvable many-body problems ''of goldfish type'' is extended by including (the additional presence of) three-body forces. The solvable N-body problems thereby identified are characterized by Newtonian equations of motion featuring 19 ...
Oksana Bihun, Francesco Calogero
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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