Results 191 to 200 of about 2,046,360 (260)

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Transient changes in body weight and behavior during the placentation period in non-human primates and rodents. [PDF]

Sci Rep
Yano-Nashimoto S, Shinozuka K, Kurachi T, Kagawa K, Sakamoto KQ, Shigeno Y, Niimi K, Kuroda KO, Yamaguchi S.   +8 more
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Food preference and behavioural choice across the eating disorder and body weight spectrum. [PDF]

J Eat Disord
Eichin KN, Arend AK, Reichenberger J, Voderholzer U, Blechert J.   +4 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Body weight-related alterations in white matter functional connectivity in children: An fMRI study. [PDF]

BMC Neurol
Huang Y, Na X, Larson-Prior L, Ou X.
europepmc   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Baseline triglyceride-cholesterol-body weight index and risk of incident cardiovascular disease: evidence from the CHARLS and ELSA cohorts. [PDF]

Front Nutr
Wang P, Qiu P, Gao B, Jiang S, Wang S.
europepmc   +1 more source

Automated body weight measurement using computed tomography. [PDF]

Sci Rep
Schenkl S, Muggenthaler H, Koch R, Heinrich A.   +3 more
europepmc   +1 more source

Effects of chronic sleep deprivation on the bone mineral density, bone microarchitecture and body weight of mice: exploratory study. [PDF]

Front Physiol
Xiang W, Lv Z, Min X, Zhang J, Yang H, Chen J, Chen J, Li D, Xu H, Luo C, Wu W.   +10 more
europepmc   +1 more source