Results 101 to 110 of about 561,084 (305)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Characteristics of smallholders’ goat production systems and effect of Boer crossbreeding on body measurements of goats in Burundi

Pastoralism, 2020
As part of a national action plan to manage animal genetic resources in Burundi, we characterized smallholders’ goat production systems and assessed the effect of Boer crossbreeding on animal body measures.
Josiane Manirakiza, Gilbert Hatungumukama, Badi Besbes, Johann Detilleux   +3 more
doaj   +1 more source

Body weight prediction of Brakmas and Bali cattle using body measurements

Malaysian Journal of Animal Science, 2016
In the rural areas facilities for farm animal weighing are often difficult to find and the construction of such facilities is relatively expensive. Therefore a study was conducted with the objective to estimate body weight of Brakmas and Bali cattle using prediction equations of linear body measurements.
Mohd. Hafiz, A.W., Izuan Bahtiar, A.J., Mohamad Hifzan, R., Ashraff, A.L., Ariff, O.M., Faezal Ashraff, A.L.   +5 more
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Anthropometric measures of obesity as risk indicators for prediabetes. A systematic review and meta-analysis

Diabetes Epidemiology and Management
Introduction: Several previous studies have provided evidence that obesity is a significant risk factor for the increase in prediabetes, but there are discrepancies regarding whether all the classic ways of measuring obesity, the body mass index (BMI ...
Víctor Juan Vera-Ponce, Fiorella E. Zuzunaga-Montoya, Luisa Erika Milagros Vásquez-Romero, Joan A. Loayza-Castro, Cori Raquel Iturregui Paucar, Carmen Inés Gutiérrez De Carrillo, Mario J. Valladares-Garrido, Maritza Placencia Medina   +7 more
doaj   +1 more source

Objectively-measured physical activity and body weight in Japanese pre-schoolers

Annals of Human Biology, 2013
The prevalence of thinness has increased among Japanese children.The purpose of this study was to examine the association between physical activity and body mass index (BMI) among Japanese pre-school children.Subjects were 425 4-6-year-old Japanese girls and boys.
Chiaki, Tanaka, Shigeho, Tanaka
openaire   +2 more sources

Genetic aspects of calving, growth, and carcass traits in beef cattle [PDF]

, 2003
The aim of this thesis was to learn more about the genetic background of calving, growth and carcass traits of beef cattle breeds in Sweden, and to assess the possibility of including calving traits and commercial carcass traits in the genetic evaluation.
Eriksson, Susanne
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Morphometry and carcass characteristics of goats submitted to grazing in the Caatinga

Revista Brasileira de Zootecnia, 2012
The objective of this study was to evaluate morphometric measures, carcass yields, absolute weights and yields of commercial cuts of carcass of kids with no defined breed. Eighteen castrated male goats, with average weight of 15 kg were used.
Sharleny Braz Lobato Bezerra, Antonia Sherlânea Chaves Véras, Dulciene Karla de Andrade Silva, Marcelo de Andrade Ferreira, Kedes Paulo Pereira, Gladston Rafael de Arruda Santos, André Luiz Rodrigues Magalhães, Omer Cavalcanti de Almeida   +7 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source