Results 131 to 140 of about 561,084 (305)

Anatomical parameters do not determine linear breaking strength or dimensions of the porcine biliary system

open access: yesBulletin of the National Research Centre
Background The porcine gall bladder and cystic duct gained attention in experimental research aimed at improving human clinical care. While the common bile duct has been investigated before, there is almost no data on the porcine cystic duct.
R. Catalina Ginghina   +10 more
doaj   +1 more source

An Investigation of Long-Term Changes in Biometric and Biochemical Parameters in a Retrospective Cohort Using Uninterrupted SGLT-2 Inhibitor Therapy

open access: yesEndocrinology Research and Practice
Objective: The study aims to examine the long-term effects of sodium-glucose Co-transporter 2 (SGLT-2) inhibitor therapy on biometric and biochemical parameters in patients with type 2 diabetes mellitus.
Emre Vuraloglu   +5 more
doaj   +1 more source

Case - Measurement of Food Consumption and Body Weight v1 [PDF]

open access: yes, 2019
Summary: During the course of development or during a diet study the amount of food and body weights are measured 1-2 times per week.
openaire   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Effectiveness and Feasibility of In-office versus Smartphone Text-delivered Nutrition Education in the College Setting: A Mixed-methods Pilot Study [PDF]

open access: yes, 2016
Often, being away from home for the first time, coupled with limited knowledge regarding healthy eating behaviors, leads to poor food choices and an increased risk of obesity among college-aged young adults.
Catlin, Anita   +3 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Crecimiento y composición corporal de las crías de ratas sometidas a restricción alimentaria

open access: yesRevista Cubana de Investigaciones Biomédicas, 1999
Nos propusimos en el presente trabajo, estudiar la influencia de la restricción alimentaria de las ratas gestantes sobre el crecimiento y el contenido de grasas y agua corporal de la prole durante los primeros 21 días de vida.
Daisy Valiente Bisset   +4 more
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

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