Results 71 to 80 of about 558,138 (246)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Body Weight Measurement in Critically Ill Patients: A Bibliometric Analysis [PDF]

Journal of Client-centered Nursing Care
Background: Determining appropriate interventions for critically ill patients requires body weight measurement. However, researchers need specific information from scientific publications to gain a more detailed insight.
Refonda Rias Anggiri, Suhartini Ismail, Retnaningsih Retnaningsih, Sumardi Sumardi   +3 more
doaj  

Type 2 diabetes, healthcare expenditures and its correlation with anthropometric factors and physical activity: 18-month follow-up in a Brazilian city

Motriz: Revista de Educacao Fisica, 2018
AIMS To compare the profile of adults attended at primary care level of the Brazilian National Health System according to occurrence of T2DM during 18 months of follow-up. METHOD Longitudinal study carried out with 316 adults.
Monique Yndawe Castanho Araujo, Bruna Camilo Turi, Dayane Cristina Queiroz, Izabela dos Santos Ferro, Carolina Rodrigues Bortolatto, Jamile Sanches Codogno   +5 more
doaj   +1 more source

Relationships between Body Measurements, Body Weight, and Productivity in Holstein Dairy Cows

Journal of Dairy Science, 1988
Abstract Body measurements, milk production, and body weight data were collected on 1898 lactations of 771 Holstein dairy cows from 1968 to 1986. Body weight and the body measurements of heart girth, paunch girth, wither height, chest depth, pelvic length, pelvic width, and body length were used. Milk production variables were milk yield, fat yield, 4%
M. Sieber, A.E. Freeman, D.H. Kelley
openaire   +1 more source

Risk of selection bias due to non-participation in a cohort study on pubertal timing. [PDF]

, 2020
BackgroundNon-participation in aetiologic studies of pubertal timing is frequent. However, little effort has been given to explore the risk and potential impact of selection bias in studies of pubertal timing.ObjectiveWe aimed to explore the risk of ...
Arah, Onyebuchi A, Brix, Nis, Ernst, Andreas, Henriksen, Tine Brink, Lauridsen, Lea Lykke Braskhøj, Olsen, Jørn, Parner, Erik Thorlund, Ramlau-Hansen, Cecilia Høst   +7 more
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A mechanistic model of connector hubs, modularity, and cognition

, 2018
The human brain network is modular--comprised of communities of tightly interconnected nodes. This network contains local hubs, which have many connections within their own communities, and connector hubs, which have connections diversely distributed ...
Bassett, Danielle S., Bertolero, Maxwell A., D'Esposito, Mark, Yeo, B. T. T.   +3 more
core   +1 more source

The effects of graded levels of calorie restriction : I. impact of short term calorie and protein restriction on body composition in the C57BL/6 mouse [PDF]

, 2015
We acknowledge the BSU staff for their invaluable help with caring for the animals and anonymous referees for their inputs. The work was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) of the UK (Standard grant BB/G009953 ...
Aspden, Richard M, Bruel, Aurélie, Chen, Luonan, Delville, Camille, Derous, Davina, Douglas, Alex, Goodyear, Simon R, Green, Cara, Han, Jackie J D, Kerbois, Celine, Konstantopedos, Penelope, Lusseau, David, Mitchell, Sharon E, Promislow, Daniel E L, Speakman, John R, Tang, Zhanhui, Wang, Yingchun   +16 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source