Results 91 to 100 of about 53,212 (199)

Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma

The FEBS Journal, EarlyView.
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture, Devi Nandana, Karthik Ramasamy, Anjan Thakurta   +3 more
wiley   +1 more source

La gestión del desplazamiento interno en Bogotá como una forma de vida

Revista Colombiana de Antropología, 2014
El artículo explora, a través de una historia de vida, cómo la gestión del desplazamiento dejó de ser una situación temporal y transicional para convertirse en un “oficio” y en un proceso de transformación subjetiva dentro de las diná- micas urbanas de ...
Leidy Paola Bolaños Florido
doaj  

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner, Manuela Albisetti, Jesús Ardila, Jan Astermark, Jan Blatny, Manuel Carcao, Pratima Chowdary, Nathan T. Connell, Miguel Crato, Yesim Dargaud, Roseline d'Oiron, Amy L. Dunn, Miguel A. Escobar, Carmen Escuriola‐Ettingshausen, Emna Gouider, Annie Harroche, Cedric Hermans, Victor Jimenez‐Yuste, Radoslaw Kaczmarek, Gili Kenet, Liane Khoo, Robert Klamroth, Florian Langer, David Lillicrap, Johnny Mahlangu, Christoph Male, Tadashi Matsushita, Sandrine Meunier, Wolfgang Miesbach, Beatrice Nolan, Johannes Oldenburg, Brian O'Mahony, Margareth Ozelo, Glenn F. Pierce, Gloria Ramos, Michael Recht, Olivia Romero‐Lux, Dawn Rotellini, Rita C. Santoro, Tammuella C. Singleton, Alok Srivastava, Sophie Susen, Kate Talks, Huyen Tran, Leonard A. Valentino, Jerzy Windyga, Renchi Yang, Maria Elisa Mancuso, also on behalf of AICE, AHAD‐AP, AHCDC, ATHN, CLAHT, EHC, French CRH & MHEMO, HTCCNC, NBDF, PEDNET, UKHCDO, WFH   +59 more
wiley   +1 more source

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

International Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli, Esteban Ulate, Hugo‐Roberto Munoz, Nestor Ríos‐Osorio   +3 more
wiley   +1 more source

Consensus on energy‐based devices for keloids and hypertrophic scars: A Latin American Delphi study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Latin American Delphi consensus supports a sequential, multimodal approach to keloids and hypertrophic scars: vascular devices for early/inflammatory lesions; intralesional triamcinolone + 5‐fluorouracil and other injectable drugs for active scars; fractional lasers for texture; and pigment‐targeting therapies for dyschromia, prioritizing safety in ...
Gisele Viana de Oliveira, Patricia Apt Druck, Alvaro Andres Luque Acevedo, Doris Hexsel, Gabriel Teixeira Gontijo, Gabriel Huerta Rivera, Luis Leobardo Velázquez‐Arenas, Flávia Alvim Sant Anna Addor, Fátima Agüero Zaputovich, Hector Leal‐Silva, Sebastian Leal‐Delgado, Carlos Echevarría Escribens, Kleber Danilo Ollague Murillo, Susana Misticone, Leandra D'orsi Metsavaht, Johnny de la Riva, Daniel Ricardo Galimberti, Silvia Karina Kaminsky Jedwab, Hector Ricardo Galván Garcia, Marcia Ramos e Silva, Mariana Rocha Andrade, Eugenio Reis‐Filho, Marcio Roberto Silva, George Krompouzos, Daniela Guzmán‐Sánchez   +24 more
wiley   +1 more source

Influence of Universal Adhesives With or Without Silane Compared to One‐Step and Two‐Step Silane Agents on Bond Strength to Lithium Disilicate

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective To evaluate the microshear bond strength (μSBS) to lithium disilicate achieved with universal adhesives (with and without silane) compared with one‐step and two‐step silanes, immediately (IM) and after thermocycling (TC). Chemical interaction (CI) was also assessed.
Camilo Pulido, Michel Wendlinger, Gabriel David Cochinski, Camila Farias Monteles, Alessandro Dourado Loguercio   +4 more
wiley   +1 more source

Differences in the Gastric Microbiotas of Neighboring Populations With Divergent Risks of Gastric Cancer

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Although Helicobacter pylori plays a central role in gastric cancer (GC), other microorganisms involved in gastric dysbiosis may also impact carcinogenesis. We aimed to characterize gastric dysbiosis and its role in the transition from non‐atrophic gastritis (NAG) to gastric premalignant lesions (GPLs) in two populations from Nariño,
Juan Camilo Caguazango, Karla Vinasco, Isidora Simovic, Yomaira Yépez Caicedo, Marino Coral Bedoya, Nadeem O. Kaakoush, Natalia Castaño‐Rodríguez   +6 more
wiley   +1 more source

A corporate turn? Insights from Colombia, the world's contemporary laboratory for transitional justice

Journal of Law and Society, EarlyView.
Abstract Corporate accountability remains marginal in transitional justice, despite growing evidence of economic actors’ complicity in armed conflicts. This article examines Colombia's transitional justice system to explain the persistent exclusion of corporate responsibility.
LINE JESPERSGAARD JAKOBSEN
wiley   +1 more source

THE LATIN AMERICAN LIBERATOR SIMÓN BOLÍVAR AT THE MUSEUM OF ART IN BOGOTÁ, COLOMBIA: TEN IMAGES BY FIVE ARTISTS

Art is on, 2018
This review compiles and analyzes a set of ten images related to the Latin-American Liberator, Simón Bolívar,that were never published as a single study.
Rafael Arreaza Scrocchi
doaj  

Rethinking Global Obesity Guidelines: Integrating Evidence, Equity and Precision (2014–2026)

Obesity Reviews, EarlyView.
Challenges and evidence in obesity guidelines. ABSTRACT Obesity remains a global health crisis characterized by substantial heterogeneity in diagnosis, management, and policy implementation. Although numerous national and international clinical practice guidelines have been published over the past decade, their translation into evidence‐based and ...
Rosero‐Revelo Ricardo, Tamayo Mateo, Henao Diana, Juan P. Polanco, Cortés David, Juan C. Alba, Giha Valeria, Camargo Camilo, Hernández Eder, Correa Ricardo, Nassar Ricardo, Cabandugama Peminda, Marcio L. Griebeler, Burguera Bartolome   +13 more
wiley   +1 more source